Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.78 |
| ▸ | POLB | P06746 | 2/20 | 0.78 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.78 |
| ▸ | GAA | P10253 | 2/20 | 0.78 |
| ▸ | MAPT | P10636 | 2/20 | 0.78 |
| ▸ | APEX1 | P27695 | 1/20 | 0.78 |
| ▸ | MPI | P34949 | 1/20 | 0.78 |
| ▸ | RECQL | P46063 | 1/20 | 0.78 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.78 |
| ▸ | SELL | P14151 | 1/20 | 0.65 |
| ▸ | SELP | P16109 | 1/20 | 0.65 |
| ▸ | SELE | P16581 | 1/20 | 0.65 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.56 |
| ▸ | ACHE | P22303 | 2/20 | 0.50 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.50 |
| ▸ | ERN1 | O75460 | 2/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.40 |
| ▸ | AKR1B1 | P15121 | 3/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | TYR | P14679 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30669742 | 0.88 | KDM4E (1.00) | ALDH1A1POLBKDM4EGAAMAPT | |
| SCHEMBL26627969 | 0.88 | KDM4E (1.00) | ALDH1A1POLBKDM4EGAAMAPT | |
| SCHEMBL10053939 | 0.82 | SELL (0.62) | ALDH1A1POLBKDM4EGAAMAPT | |
| Cordyol C SCHEMBL29979417 | 0.81 | POLB (0.60) | ALDH1A1POLBKDM4EGAAMAPT | |
| SCHEMBL67584 | 0.80 | SELL (1.00) | ALDH1A1POLBKDM4EGAAMAPT | |
| SCHEMBL6634379 | 0.78 | GLO1 (0.54) | ALDH1A1POLBKDM4EGAAMAPT | |
| Methoxymethane SCHEMBL11591595 | 0.78 | SELL (0.82) | ALDH1A1POLBKDM4EGAAMAPT | |
| SCHEMBL20414730 | 0.77 | ALDH1A1 (0.55) | ALDH1A1POLBKDM4EGAAMAPT | |
| SCHEMBL6244864 | 0.75 | SMN1; SMN2 (0.68) | ALDH1A1POLBKDM4EGAAMAPT | |
| SCHEMBL30898481 | 0.75 | SMN1; SMN2 (0.68) | ALDH1A1POLBKDM4EGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116162668-B | Preparation method and application of diphenyl ether compound | 广西中医药大学 | 2024-12-17 | — | — | CN | claimed |
| CN-116162668-B | Preparation method and application of diphenyl ether compound | 广西中医药大学 | 2024-12-17 | — | — | CN | disclosed |
| CN-116162668-B | Preparation method and application of diphenyl ether compound | 广西中医药大学 | 2024-12-17 | — | — | CN | disclosed |
| CN-118161469-A | Application of phenolic compound in preparation of medicine for preventing and treating necrosis-like apoptosis diseases and medicine thereof | 福建师范大学 | 2024-06-11 | — | — | CN | disclosed |
| US-20230338340-A1 | Methods of Treating Cystic Fibrosis | DARTMOUTH COLLEGE (US) | 2023-10-26 | — | — | US | disclosed |
| US-20230338340-A1 | Methods of Treating Cystic Fibrosis | DARTMOUTH COLLEGE (US) | 2023-10-26 | — | — | US | disclosed |
| US-20230338340-A1 | Methods of Treating Cystic Fibrosis | DARTMOUTH COLLEGE (US) | 2023-10-26 | — | — | US | disclosed |
| CN-116162668-A | Preparation method and application of diphenyl ether compound | 广西中医药大学 | 2023-05-26 | — | — | CN | disclosed |
| CN-116162668-A | Preparation method and application of diphenyl ether compound | 广西中医药大学 | 2023-05-26 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230338340-A1 | Methods of Treating Cystic Fibrosis | CFTR, DAB2IP, CTTN | ALDH1A1 3332/4885POLB 4458/4885KDM4E 4381/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.