Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 4/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | MAPT | P10636 | 3/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.60 |
| ▸ | RECQL | P46063 | 2/20 | 0.60 |
| ▸ | GAA | P10253 | 1/20 | 0.60 |
| ▸ | APEX1 | P27695 | 1/20 | 0.60 |
| ▸ | MPI | P34949 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.56 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.54 |
| ▸ | SELL | P14151 | 1/20 | 0.48 |
| ▸ | SELP | P16109 | 1/20 | 0.48 |
| ▸ | SELE | P16581 | 1/20 | 0.48 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29807406 | 0.82 | HCAR1 (0.54) | POLBALDH1A1MAPTKDM4ERECQL | |
| SCHEMBL28367094 | 0.82 | HCAR1 (0.54) | POLBALDH1A1MAPTKDM4ERECQL | |
| SCHEMBL9945605 | 0.81 | PTPN1 (0.49) | POLBALDH1A1MAPTKDM4ERECQL | |
| Diorcinol SCHEMBL29629136 | 0.81 | ALDH1A1 (0.60) | POLBALDH1A1MAPTKDM4ERECQL | |
| Diorcinol SCHEMBL28744720 | 0.81 | ALDH1A1 (0.60) | POLBALDH1A1MAPTKDM4ERECQL | |
| SCHEMBL26627967 | 0.81 | ALDH1A1 (0.78) | POLBALDH1A1MAPTKDM4ERECQL | |
| SCHEMBL26627969 | 0.75 | KDM4E (1.00) | POLBALDH1A1MAPTKDM4ERECQL | |
| SCHEMBL30669742 | 0.75 | KDM4E (1.00) | POLBALDH1A1MAPTKDM4ERECQL | |
| SCHEMBL29884664 | 0.75 | GLO1 (0.74) | POLBALDH1A1MAPTKDM4ERECQL | |
| SCHEMBL29934320 | 0.74 | PTPN1 (0.45) | POLBALDH1A1MAPTKDM4ERECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112843026-B | Application of diphenyl ether compound in preparation of acetylcholinesterase inhibitor or medicament for treating Alzheimer disease | 中国科学院南海海洋研究所 | 2022-11-04 | — | — | CN | disclosed |
| CN-112843026-B | Application of diphenyl ether compound in preparation of acetylcholinesterase inhibitor or medicament for treating Alzheimer disease | 中国科学院南海海洋研究所 | 2022-11-04 | — | — | CN | disclosed |