Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.51 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.49 |
| ▸ | RARB | P10826 | 1/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3503996 | 0.87 | ALDH1A1 (0.81) | ALDH1A1KMT2ASMN1; SMN2KDM4EL3MBTL1 | |
| Hydrochloric Acid SCHEMBL15392980 | 0.85 | ALDH1A1 (0.78) | ALDH1A1KMT2ASMN1; SMN2KDM4EL3MBTL1 | |
| Terephthalic Acid SCHEMBL31728724 | 0.85 | ALDH1A1 (0.60) | ALDH1A1KMT2ASMN1; SMN2KDM4EHPGD | |
| Terephthalic Acid SCHEMBL27842309 | 0.85 | ALDH1A1 (0.60) | ALDH1A1KMT2ASMN1; SMN2KDM4EHPGD | |
| Diethylamine SCHEMBL11526218 | 0.84 | ALDH1A1 (0.80) | ALDH1A1KMT2ASMN1; SMN2POLBRARB | |
| SCHEMBL18602133 | 0.84 | KMT2A (0.57) | ALDH1A1KMT2ASMN1; SMN2L3MBTL1NR1H4 | |
| SCHEMBL2938207 | 0.83 | ALDH1A1 (0.69) | ALDH1A1KMT2ASMN1; SMN2KDM4EL3MBTL1 | |
| SCHEMBL21505918 | 0.83 | SMN1; SMN2 (0.55) | ALDH1A1SMN1; SMN2KDM4EL3MBTL1HPGD | |
| SCHEMBL18235891 | 0.82 | EPHX2 (0.53) | ALDH1A1KMT2ASMN1; SMN2KDM4ENR1H4 | |
| SCHEMBL18828911 | 0.82 | S1PR1 (0.57) | ALDH1A1KMT2ASMN1; SMN2RARB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118185434-B | Weather-resistant powder coating and preparation method thereof | 中山虹丽美新材料科技有限公司 | 2024-08-13 | — | — | CN | claimed |
| CN-118185434-A | Weather-resistant powder coating and preparation method thereof | 中山虹丽美新材料科技有限公司 | 2024-06-14 | — | — | CN | claimed |
| US-12371401-B2 | Dithienyl disulfiram derivatives as selective ALDH1A1 inhibitors | BATTERJEE MEDICAL COLLEGE (SA) | 2025-07-29 | — | — | US | disclosed |
| US-20250145565-A1 | DITHIENYL DISULFIRAM DERIVATIVES AS SELECTIVE ALDH1A1 INHIBITORS | BATTERJEE MEDICAL COLLEGE (SA) | 2025-05-08 | — | — | US | disclosed |
| US-12227469-B2 | Disulfiram derivatives as ALDH1a1 and MAGL inhibitors | BATTERJEE MEDICAL COLLEGE (SA) | 2025-02-18 | — | — | US | disclosed |
| CN-118185434-B | Weather-resistant powder coating and preparation method thereof | 中山虹丽美新材料科技有限公司 | 2024-08-13 | — | — | CN | disclosed |
| CN-118185434-A | Weather-resistant powder coating and preparation method thereof | 中山虹丽美新材料科技有限公司 | 2024-06-14 | — | — | CN | disclosed |
| US-11753371-B2 | Disulfiram derivatives as ALDH1A1 and MAGL inhibitors | BATTERJEE MEDICAL COLLEGE (SA) | 2023-09-12 | — | — | US | disclosed |
| US-11753371-B2 | Disulfiram derivatives as ALDH1A1 and MAGL inhibitors | BATTERJEE MEDICAL COLLEGE (SA) | 2023-09-12 | — | — | US | disclosed |
| US-11753371-B2 | Disulfiram derivatives as ALDH1A1 and MAGL inhibitors | BATTERJEE MEDICAL COLLEGE (SA) | 2023-09-12 | — | — | US | disclosed |
| CN-111205244-B | Thiazolo-ring compound, preparation method, intermediate and application thereof | 上海科技大学 | 2023-08-18 | — | — | CN | disclosed |
| EP-2822941-B1 | BENZODIOXANES IN COMBINATION WITH STATINS FOR INHIBITING LEUKOTRIENE PRODUCTION | BOEHRINGER INGELHEIM INT (DE) | 2017-05-10 | — | — | EP | disclosed |
| US-9527828-B2 | Method for expanding hematopoietic stem cells using heterocyclic compound | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2016-12-27 | — | — | US | disclosed |
| US-20120077711-A1 | Novel Ligands and Libraries of Ligands | SUNESIS PHARMACEUTICALS, INC. (US) | 2012-03-29 | — | — | US | disclosed |
| US-8088805-B2 | Inhibitors of histone deacetylase | METHYLGENE INC. (CA) | 2012-01-03 | — | — | US | disclosed |
| US-20100266556-A1 | METHOD FOR EXPANDING HEMATOPOIETIC STEM CELLS USING HETEROCYCLIC COMPOUND | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 2010-10-21 | — | — | US | disclosed |
| US-7408025-B2 | Lipopeptides as antibacterial agents | CUBIST PHARMACEUTICALS, INC. (US) | 2008-08-05 | — | — | US | disclosed |
| US-20070213330-A1 | Anticancer agents; antiproliferative agents | METHYLGENE INC. (CA) | 2007-09-13 | — | — | US | disclosed |
| US-7253204-B2 | Antiproliferative agents | METHYLGENE INC. (CA) | 2007-08-07 | — | — | US | disclosed |
| WO-2000069810-A1 | GLUCAGON ANTAGONISTS/INVERSE AGONISTS | NOVO NORDISK A/S (DK) | 2000-11-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12371401-B2 | Dithienyl disulfiram derivatives as selective ALDH1A1 inhibitors | ALDH3A1, ALDH1A1, ADH1A | ALDH1A1 2/4885KMT2A 2062/4885SMN1; SMN2 654/4885 |
| US-20070213330-A1 | Anticancer agents; antiproliferative agents | HDAC1, HDAC11, HDAC5 | ALDH1A1 680/4885KMT2A 68/4885SMN1; SMN2 3557/4885 |
| US-20100266556-A1 | METHOD FOR EXPANDING HEMATOPOIETIC STEM CELLS USING HETEROCYCLIC COMPOUND | HCLS1, RUNX1, ACIN1 | ALDH1A1 256/4885KMT2A 1350/4885SMN1; SMN2 574/4885 |
| US-11753371-B2 | Disulfiram derivatives as ALDH1A1 and MAGL inhibitors | ALDH1A1, ADH1A, ALDH3A1 | ALDH1A1 1/4885KMT2A 1086/4885SMN1; SMN2 914/4885 |
| US-12227469-B2 | Disulfiram derivatives as ALDH1a1 and MAGL inhibitors | ADH1A, ALDH1A1, ALDH3A1 | ALDH1A1 2/4885KMT2A 866/4885SMN1; SMN2 1691/4885 |
| US-20250145565-A1 | DITHIENYL DISULFIRAM DERIVATIVES AS SELECTIVE ALDH1A1 INHIBITORS | ALDH3A1, ALDH1A1, ADH1A | ALDH1A1 2/4885KMT2A 2062/4885SMN1; SMN2 654/4885 |
| US-20120077711-A1 | Novel Ligands and Libraries of Ligands | LSS, ABCG2, SELL | ALDH1A1 533/4885KMT2A 4667/4885SMN1; SMN2 4117/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.