Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HLCS | P50747 | 5/20 | 0.68 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.65 |
| ▸ | PKM | P14618 | 2/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | ABL1 | P00519 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | IDE | P14735 | 1/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.61 |
| ▸ | CA12 | O43570 | 4/20 | 0.60 |
| ▸ | CA1 | P00915 | 4/20 | 0.60 |
| ▸ | CA2 | P00918 | 4/20 | 0.60 |
| ▸ | CA9 | Q16790 | 4/20 | 0.60 |
| ▸ | F2 | P00734 | 1/20 | 0.54 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.54 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.54 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.54 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23723306 | 1.00 | HLCS (0.68) | HLCSTDP1PKMMEN1ABL1 | |
| SCHEMBL16747698 | 0.94 | HLCS (0.70) | HLCSTDP1PKMMEN1ABL1 | |
| SCHEMBL23555455 | 0.94 | HLCS (0.72) | HLCSTDP1PKMMEN1ABL1 | |
| SCHEMBL3177675 | 0.90 | TDP1 (0.66) | HLCSTDP1PKMMEN1ABL1 | |
| SCHEMBL9412852 | 0.90 | TDP1 (0.74) | HLCSTDP1PKMMEN1ABL1 | |
| SCHEMBL13123264 | 0.89 | TDP1 (0.60) | HLCSTDP1PKMMEN1ABL1 | |
| SCHEMBL10014930 | 0.89 | F2 (0.65) | HLCSTDP1PKMMEN1ABL1 | |
| SCHEMBL23777451 | 0.89 | TDP1 (0.65) | HLCSTDP1PKMMEN1ABL1 | |
| SCHEMBL24040258 | 0.89 | TDP1 (0.65) | HLCSTDP1PKMMEN1ABL1 | |
| SCHEMBL21606801 | 0.89 | TDP1 (0.65) | HLCSTDP1PKMMEN1ABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12578335-B2 | Bioprobes for lysyl oxidases and uses thereof | SYNTARA LIMITED (AU) | 2026-03-17 | — | — | US | disclosed |
| US-20230349907-A1 | BIOPROBES FOR LYSYL OXIDASES AND USES THEREOF | PHARMAXIS LTD. (AU) | 2023-11-02 | — | — | US | disclosed |
| US-20230349907-A1 | BIOPROBES FOR LYSYL OXIDASES AND USES THEREOF | PHARMAXIS LTD. (AU) | 2023-11-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230349907-A1 | BIOPROBES FOR LYSYL OXIDASES AND USES THEREOF | MAOB, LOX, LPO | HLCS 45/4885TDP1 587/4885PKM 2307/4885 |
| US-12578335-B2 | Bioprobes for lysyl oxidases and uses thereof | LOXL1, LOX, LOXL2 | HLCS 76/4885TDP1 2300/4885PKM 4371/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.