Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | CASP6 | P55212 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.42 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.42 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30634263 | 0.81 | CCNC (0.47) | ALDH1A1KDM4EGAACASP6CYP3A4 | |
| SCHEMBL26634034 | 0.80 | MIF (0.51) | ALDH1A1KDM4EGAACYP3A4MEN1 | |
| SCHEMBL26634035 | 0.80 | PDGFRB (0.57) | ALDH1A1KDM4EGAACYP3A4MEN1 | |
| SCHEMBL3173460 | 0.79 | MAPT (0.52) | ALDH1A1KDM4EGAACYP3A4MEN1 | |
| SCHEMBL3173449 | 0.79 | MAPT (0.52) | ALDH1A1KDM4EGAACYP3A4MEN1 | |
| SCHEMBL3412523 | 0.79 | CASP6 (0.57) | ALDH1A1KDM4EGAACASP6DOT1L | |
| SCHEMBL26634056 | 0.78 | LMNA (0.40) | ALDH1A1KDM4EGAAMEN1KMT2A | |
| SCHEMBL2385880 | 0.78 | CYP3A4 (0.74) | ALDH1A1KDM4EGAACYP3A4MEN1 | |
| SCHEMBL2385888 | 0.78 | CYP3A4 (0.74) | ALDH1A1KDM4EGAACYP3A4MEN1 | |
| SCHEMBL26634022 | 0.77 | KDR (0.44) | ALDH1A1KDM4EGAAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023212565-A2 | MOLECULAR EDITING OF MULTIPLE C-H BONDS BY LEVERAGING RECOGNITION OF DISTANCE, GEOMETRY AND CHIRALITY | THE SCRIPPS RESEARCH INSTITUTE (US) | 2023-11-02 | — | — | WO | disclosed |