Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 1/20 | 0.57 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.52 |
| ▸ | GAA | P10253 | 4/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30634255 | 0.84 | PDGFRB (0.51) | PDGFRBPDGFRAALDH1A1KDM4EGAA | |
| SCHEMBL12809651 | 0.82 | GAA (0.56) | ALDH1A1KDM4EGAAMEN1KMT2A | |
| SCHEMBL26633964 | 0.80 | ALDH1A1 (0.49) | ALDH1A1KDM4EGAAMEN1KMT2A | |
| SCHEMBL26633986 | 0.77 | DPP4 (0.43) | PDGFRAALDH1A1KDM4EGAAMEN1 | |
| SCHEMBL26634034 | 0.77 | MIF (0.51) | ALDH1A1KDM4EGAAMEN1KMT2A | |
| SCHEMBL3953895 | 0.76 | PDGFRB (0.66) | PDGFRBPDGFRAALDH1A1KDM4EMEN1 | |
| SCHEMBL29488239 | 0.76 | PDGFRB (0.66) | PDGFRBPDGFRAALDH1A1KDM4EALOX15 | |
| SCHEMBL3953893 | 0.76 | PDGFRB (0.66) | PDGFRBPDGFRAALDH1A1KDM4EMEN1 | |
| SCHEMBL6852559 | 0.76 | NFE2L2 (0.69) | ALDH1A1KDM4EGAAMEN1KMT2A | |
| SCHEMBL6852555 | 0.76 | NFE2L2 (0.69) | ALDH1A1KDM4EGAAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023212565-A2 | MOLECULAR EDITING OF MULTIPLE C-H BONDS BY LEVERAGING RECOGNITION OF DISTANCE, GEOMETRY AND CHIRALITY | THE SCRIPPS RESEARCH INSTITUTE (US) | 2023-11-02 | — | — | WO | disclosed |