Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MIF | P14174 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.42 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.41 |
| ▸ | CCNC | P24863 | 2/20 | 0.40 |
| ▸ | CDK8 | P49336 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | PLK1 | P53350 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30634280 | 0.81 | CCNC (0.47) | CYP3A4RAB9AALDH1A1KDM4EGAA | |
| SCHEMBL26633964 | 0.80 | ALDH1A1 (0.49) | CYP3A4RAB9AALDH1A1KDM4EGAA | |
| SCHEMBL16523380 | 0.79 | KDM4E (0.51) | CYP3A4RAB9AALDH1A1KDM4EGAA | |
| SCHEMBL3174017 | 0.79 | MAPT (0.52) | CYP3A4RAB9AALDH1A1KDM4EGAA | |
| SCHEMBL3174004 | 0.79 | MAPT (0.52) | CYP3A4RAB9AALDH1A1KDM4EGAA | |
| SCHEMBL2169868 | 0.79 | NPC1 (0.47) | RAB9AALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL2385888 | 0.78 | CYP3A4 (0.74) | CYP3A4RAB9AALDH1A1KDM4EGAA | |
| SCHEMBL2385880 | 0.78 | CYP3A4 (0.74) | CYP3A4RAB9AALDH1A1KDM4EGAA | |
| SCHEMBL26634035 | 0.77 | PDGFRB (0.57) | CYP3A4RAB9AALDH1A1KDM4EGAA | |
| SCHEMBL3173460 | 0.76 | MAPT (0.52) | CYP3A4RAB9AALDH1A1KDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023212565-A2 | MOLECULAR EDITING OF MULTIPLE C-H BONDS BY LEVERAGING RECOGNITION OF DISTANCE, GEOMETRY AND CHIRALITY | THE SCRIPPS RESEARCH INSTITUTE (US) | 2023-11-02 | — | — | WO | disclosed |