Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.51 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | HTT | P42858 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 2/20 | 0.42 |
| ▸ | MPO | P05164 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | KDM5A | P29375 | 1/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | NSD2 | O96028 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2664110 | 0.82 | APP (0.54) | ALDH1A1SMPD1KDM4EMAPTHTT | |
| SCHEMBL2664428 | 0.76 | MEN1 (0.66) | ALDH1A1CYP1A2KDM4EMAPTHTT | |
| SCHEMBL21434732 | 0.76 | ALDH1A1 (0.62) | ALDH1A1CYP1A2CYP2C9KDM4EMAPT | |
| SCHEMBL11786660 | 0.72 | CYP1A2 (0.46) | ALDH1A1CYP1A2CYP2C9KDM4EMAPT | |
| SCHEMBL14556328 | 0.72 | TTR (0.53) | ALDH1A1KDM4EMAPTMEN1KMT2A | |
| SCHEMBL2664433 | 0.71 | HDAC6 (0.67) | ALDH1A1KDM4EMAPTHTTBLM | |
| SCHEMBL31472702 | 0.71 | HDAC6 (0.67) | ALDH1A1KDM4EMAPTHTTBLM | |
| SCHEMBL18882511 | 0.71 | AR (0.46) | ALDH1A1CYP1A2CYP2C9KDM4EMAPT | |
| SCHEMBL11786107 | 0.71 | MEN1 (0.59) | ALDH1A1CYP1A2CYP2C9KDM4EMAPT | |
| SCHEMBL4275043 | 0.71 | L3MBTL1 (0.56) | ALDH1A1KDM4EMAPTHTTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999001423-A1 | GLUCAGON ANTAGONISTS/INVERSE AGONISTS | NOVO NORDISK A/S (DK) | 1999-01-14 | — | — | WO | disclosed |