Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 7/20 | 0.54 |
| ▸ | GCGR | P47871 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 2/20 | 0.44 |
| ▸ | MPO | P05164 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | KDM5A | P29375 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | NSD2 | O96028 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | ALPL | P05186 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | ALPI | P09923 | 1/20 | 0.43 |
| ▸ | ALPG | P10696 | 1/20 | 0.43 |
| ▸ | APEX1 | P27695 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3641624 | 0.82 | APP (0.50) | APPGCGRHTTKMT2A | |
| SCHEMBL2663965 | 0.82 | ALDH1A1 (0.51) | BLMMPOCYP3A4KDM5AGFER | |
| SCHEMBL3648979 | 0.80 | HTT (0.61) | APPGCGRALDH1A1KDM4EMAPT | |
| SCHEMBL10321468 | 0.79 | CA12 (0.59) | APPGCGRALDH1A1KDM4EMAPT | |
| SCHEMBL2664428 | 0.79 | MEN1 (0.66) | BLMALDH1A1KDM4EMAPTGAA | |
| SCHEMBL10322973 | 0.79 | APP (0.50) | APPGCGRLMNAHTTKMT2A | |
| SCHEMBL24436791 | 0.78 | APP (0.50) | APPGCGRBLMALDH1A1KDM4E | |
| SCHEMBL2650529 | 0.75 | TRPV1 (0.59) | BLMMPOCYP3A4KDM5AGFER | |
| SCHEMBL14556328 | 0.74 | TTR (0.53) | APPALDH1A1KDM4EMAPTPOLB | |
| SCHEMBL2664433 | 0.74 | HDAC6 (0.67) | BLMMPOCYP3A4KDM5AGFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999001423-A1 | GLUCAGON ANTAGONISTS/INVERSE AGONISTS | NOVO NORDISK A/S (DK) | 1999-01-14 | — | — | WO | disclosed |