Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 5/20 | 0.43 |
| ▸ | CRBN | Q96SW2 | 5/20 | 0.43 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | ADAMTS5 | Q9UNA0 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MMP2 | P08253 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TNKS | O95271 | 2/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30643667 | 0.84 | DDB1 (0.49) | DDB1CRBNMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL26641815 | 0.83 | ADRB1 (0.54) | DDB1CRBNMAPTALDH1A1HTT | |
| SCHEMBL29007105 | 0.82 | CRBN (0.59) | DDB1CRBNMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL23983379 | 0.77 | TYMP (0.39) | DDB1CRBNMAPTALDH1A1HTT | |
| SCHEMBL28978059 | 0.76 | HPGD (0.44) | DDB1CRBNSMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL23121262 | 0.75 | CRBN (0.48) | DDB1CRBNMAPTALDH1A1MEN1 | |
| SCHEMBL29607217 | 0.75 | CRBN (0.48) | DDB1CRBNMAPTALDH1A1MEN1 | |
| SCHEMBL23984161 | 0.75 | LMNA (0.39) | DDB1CRBNMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL25666847 | 0.75 | DDB1 (0.39) | DDB1CRBNALDH1A1HTTADAMTS5 | |
| SCHEMBL631834 | 0.74 | MAPT (0.68) | MAPTSMN1; SMN2ALDH1A1GFERHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023220640-A1 | CDK PROTEIN DEGRADERS, PHARMACEUTICAL COMPOSITIONS, AND THERAPEUTIC APPLICATIONS | BIOTHERYX, INC. (US) | 2023-11-16 | — | — | WO | disclosed |