Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 | P08588 | 6/20 | 0.54 |
| ▸ | DDB1 | Q16531 | 6/20 | 0.46 |
| ▸ | CRBN | Q96SW2 | 6/20 | 0.46 |
| ▸ | HTR3E | A5X5Y0 | 3/20 | 0.46 |
| ▸ | HTR3B | O95264 | 3/20 | 0.46 |
| ▸ | HTR3A | P46098 | 3/20 | 0.46 |
| ▸ | HTR3D | Q70Z44 | 3/20 | 0.46 |
| ▸ | HTR3C | Q8WXA8 | 3/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | HTR6 | P50406 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | HTR2C | P28335 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30266979 | 0.90 | ADRB1 (0.54) | ADRB1DDB1CRBNHTR3EHTR3B | |
| SCHEMBL27039567 | 0.84 | DDB1 (0.56) | ADRB1DDB1CRBNHTR3EHTR3B | |
| SCHEMBL27039415 | 0.84 | CRBN (0.46) | ADRB1DDB1CRBNHTR3EHTR3B | |
| Hydrochloric Acid SCHEMBL30969010 | 0.83 | DDB1 (0.55) | ADRB1DDB1CRBNHTR3EHTR3B | |
| SCHEMBL26641240 | 0.83 | DDB1 (0.43) | DDB1CRBNHTTTP53ALDH1A1 | |
| SCHEMBL31306692 | 0.82 | DDB1 (0.56) | ADRB1DDB1CRBNHTR3EHTR3B | |
| SCHEMBL25824550 | 0.81 | HTR1A (0.44) | ADRB1DDB1CRBNHTR3EHTR3B | |
| SCHEMBL26641696 | 0.81 | HTR3E (0.43) | ADRB1DDB1CRBNHTR3EHTR3B | |
| SCHEMBL22119794 | 0.80 | CRBN (0.65) | ADRB1DDB1CRBNHTR3EHTR3B | |
| SCHEMBL23983379 | 0.79 | TYMP (0.39) | DDB1CRBNHTTALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120092003-A | CDK protein degrading agents, pharmaceutical compositions and therapeutic uses | 拜欧斯瑞克斯公司 | 2025-06-03 | — | — | CN | disclosed |
| WO-2023220640-A1 | CDK PROTEIN DEGRADERS, PHARMACEUTICAL COMPOSITIONS, AND THERAPEUTIC APPLICATIONS | BIOTHERYX, INC. (US) | 2023-11-16 | — | — | WO | disclosed |