Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 6/20 | 0.41 |
| ▸ | MTOR | P42345 | 6/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.40 |
| ▸ | DPP4 | P27487 | 1/20 | 0.39 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.39 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.39 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.39 |
| ▸ | TRPC6 | Q9Y210 | 2/20 | 0.38 |
| ▸ | GCK | P35557 | 2/20 | 0.38 |
| ▸ | GCKR | Q14397 | 1/20 | 0.38 |
| ▸ | CDK1 | P06493 | 1/20 | 0.37 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.37 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23089626 | 1.00 | PIK3CA (0.41) | PIK3CAMTORHRH3DPP4DPP8 | |
| SCHEMBL23089627 | 1.00 | PIK3CA (0.41) | PIK3CAMTORHRH3DPP4DPP8 | |
| SCHEMBL23089168 | 0.86 | PIK3CA (0.37) | PIK3CAMTORHRH3TRPC6GCK | |
| SCHEMBL29814459 | 0.86 | PIK3CA (0.37) | PIK3CAMTORHRH3TRPC6GCK | |
| SCHEMBL24747233 | 0.85 | CHRNB2 (0.40) | PIK3CAMTORHRH3DPP4DPP8 | |
| SCHEMBL30316003 | 0.85 | CHRNB2 (0.40) | PIK3CAMTORHRH3DPP4DPP8 | |
| SCHEMBL23107220 | 0.84 | USP1 (0.42) | PIK3CAMTORHRH3DPP4DPP8 | |
| SCHEMBL25558878 | 0.84 | DPP4 (0.41) | PIK3CAMTORDPP4DPP8DPP9 | |
| SCHEMBL13768902 | 0.83 | CDK4 (0.48) | PIK3CAMTORHRH3TRPC6 | |
| SCHEMBL31607811 | 0.82 | TRPC6 (0.39) | PIK3CAMTORHRH3DPP4DPP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119874700-A | HPK1 antagonists and uses thereof | 林伯士萨顿公司 | 2025-04-25 | — | — | CN | disclosed |
| CN-114945366-B | HPK1 antagonists and uses thereof | 林伯士萨顿公司 | 2025-01-07 | — | — | CN | disclosed |
| CN-114945366-A | HPK1 antagonists and uses thereof | 林伯士萨顿公司 | 2022-08-26 | — | — | CN | disclosed |