Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.46 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.45 |
| ▸ | TAOK1 | Q7L7X3 | 1/20 | 0.45 |
| ▸ | TAOK3 | Q9H2K8 | 1/20 | 0.45 |
| ▸ | PPARD | Q03181 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4630807 | 0.82 | HTR2C (0.61) | MAOBAOC3HRH3TAOK1TAOK3 | |
| SCHEMBL5880760 | 0.76 | RAB9A (0.53) | ALDH1A1EPHX2KDM4EPOLB | |
| SCHEMBL10938284 | 0.76 | SMN1; SMN2 (0.55) | ALDH1A1EPHX2MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL2255074 | 0.75 | EPHX2 (0.53) | KDM2BHRH3TDP1L3MBTL1ALDH1A1 | |
| SCHEMBL656941 | 0.75 | ALOX15 (0.59) | MAOBAOC3HRH3PPARDPPARA | |
| SCHEMBL2171542 | 0.74 | MAOB (0.57) | MAOBAOC3HRH3TDP1ALDH1A1 | |
| SCHEMBL118361 | 0.74 | MAOB (0.53) | MAOBAOC3HRH3TDP1L3MBTL1 | |
| SCHEMBL12824120 | 0.74 | ALDH1A1 (0.54) | MAOBAOC3HRH3PPARDL3MBTL1 | |
| SCHEMBL18960368 | 0.73 | EPHX2 (0.64) | TDP1L3MBTL1ALDH1A1EPHX2EPHX1 | |
| SCHEMBL2554073 | 0.72 | POLB (0.56) | TDP1L3MBTL1ALDH1A1CYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999001423-A1 | GLUCAGON ANTAGONISTS/INVERSE AGONISTS | NOVO NORDISK A/S (DK) | 1999-01-14 | — | — | WO | disclosed |