Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.32 |
| ▸ | CASP3 | P42574 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26644664 | 1.00 | CD274 (0.32) | CD274CASP3CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL26644661 | 1.00 | CD274 (0.32) | CD274CASP3CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL17024344 | 0.83 | EPHX2 (0.39) | CD274 | |
| SCHEMBL29268531 | 0.73 | OPRD1 (0.42) | CASP3 | |
| SCHEMBL10048579 | 0.72 | FABP5 (0.44) | CASP3CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL10016953 | 0.72 | FABP5 (0.44) | CASP3CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL7361552 | 0.71 | — | — | |
| SCHEMBL14377686 | 0.71 | FABP5 (0.37) | CASP3TSHR | |
| SCHEMBL9740757 | 0.71 | EPHX2 (0.34) | — | |
| SCHEMBL2583781 | 0.70 | EPHX2 (0.43) | CASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230357320-A1 | HELICAL STAPLED PEPTIDES AND USES THEREOF | PARABILIS MEDICINES, INC. | 2023-11-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230357320-A1 | HELICAL STAPLED PEPTIDES AND USES THEREOF | ESRRB, ESR1, ESRRA | CD274 821/4885CASP3 1532/4885CYP1A2 4868/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.