Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 4/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | CYP3A5 | P20815 | 2/20 | 0.46 |
| ▸ | CSNK1E | P49674 | 6/20 | 0.45 |
| ▸ | CSNK1D | P48730 | 4/20 | 0.45 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.42 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | STS | P08842 | 1/20 | 0.40 |
| ▸ | DPP4 | P27487 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 2/20 | 0.39 |
| ▸ | CNR2 | P34972 | 2/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26645116 | 0.84 | CYP3A4 (0.45) | RORCCYP3A4CYP3A5CSNK1ECSNK1D | |
| SCHEMBL26645364 | 0.83 | CSNK1E (0.45) | RORCCYP3A4CYP3A5CSNK1ECSNK1D | |
| SCHEMBL16711450 | 0.81 | CSNK1E (0.52) | CSNK1ECSNK1DMEN1KMT2A | |
| SCHEMBL16711190 | 0.79 | CSNK1E (0.55) | CSNK1ECSNK1D | |
| SCHEMBL30623018 | 0.79 | CSNK1E (0.44) | CSNK1ECSNK1DSTS | |
| SCHEMBL26645586 | 0.79 | CSNK1E (0.44) | CSNK1ECSNK1DSTS | |
| SCHEMBL26645345 | 0.79 | CYP3A4 (0.48) | RORCCYP3A4CYP3A5USP30MKNK1 | |
| SCHEMBL26645590 | 0.79 | CYP3A4 (0.41) | RORCCYP3A4CYP3A5CSNK1ECSNK1D | |
| SCHEMBL26645023 | 0.78 | MERTK (0.43) | CSNK1ECSNK1DMEN1KMT2A | |
| SCHEMBL30622820 | 0.77 | CYP3A4 (0.43) | RORCCYP3A4CYP3A5CSNK1ECSNK1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4519265-A1 | IRREVERSIBLE MUTEGFR INHIBITORS | Bayer Aktiengesellschaft (DE) | 2025-03-12 | — | — | EP | disclosed |
| WO-2023213882-A1 | IRREVERSIBLE MUTEGFR INHIBITORS | BAYER AKTIENGESELLSCHAFT (DE) | 2023-11-09 | — | — | WO | disclosed |