Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MERTK | Q12866 | 1/20 | 0.43 |
| ▸ | CSNK1D | P48730 | 3/20 | 0.42 |
| ▸ | CSNK1E | P49674 | 3/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CACNB4 | O00305 | 2/20 | 0.39 |
| ▸ | CACNA1A | O00555 | 2/20 | 0.39 |
| ▸ | CACNA1G | O43497 | 2/20 | 0.39 |
| ▸ | CACNG3 | O60359 | 2/20 | 0.39 |
| ▸ | CACNA1F | O60840 | 2/20 | 0.39 |
| ▸ | CACNA1H | O95180 | 2/20 | 0.39 |
| ▸ | CACNB3 | P54284 | 2/20 | 0.39 |
| ▸ | CACNA2D1 | P54289 | 2/20 | 0.39 |
| ▸ | CACNG7 | P62955 | 2/20 | 0.39 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.39 |
| ▸ | CACNA1D | Q01668 | 2/20 | 0.39 |
| ▸ | CACNB1 | Q02641 | 2/20 | 0.39 |
| ▸ | CACNG1 | Q06432 | 2/20 | 0.39 |
| ▸ | CACNB2 | Q08289 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26645106 | 0.84 | CSNK1D (0.42) | MERTKCSNK1DCSNK1EMAPK1APLNR | |
| SCHEMBL26645223 | 0.81 | ALDH1A1 (0.48) | CSNK1EMEN1KMT2AALDH1A1 | |
| SCHEMBL26645413 | 0.81 | SUV39H2 (0.44) | CSNK1EALKMAPK1CACNB4CACNA1A | |
| SCHEMBL26645586 | 0.81 | CSNK1E (0.44) | CSNK1DCSNK1EALKGRM5GRM1 | |
| SCHEMBL30622957 | 0.81 | SUV39H2 (0.44) | CSNK1EALKMAPK1CACNB4CACNA1A | |
| SCHEMBL30623018 | 0.81 | CSNK1E (0.44) | CSNK1DCSNK1EALKGRM5GRM1 | |
| SCHEMBL16711450 | 0.80 | CSNK1E (0.52) | CSNK1DCSNK1EMEN1KMT2A | |
| SCHEMBL26645129 | 0.78 | RORC (0.47) | CSNK1DCSNK1EMEN1KMT2A | |
| SCHEMBL23389905 | 0.78 | GRM5 (0.42) | CSNK1DCSNK1EMAPK1GRM5 | |
| SCHEMBL29796687 | 0.78 | GRM5 (0.42) | CSNK1DCSNK1EMAPK1GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4519265-A1 | IRREVERSIBLE MUTEGFR INHIBITORS | Bayer Aktiengesellschaft (DE) | 2025-03-12 | — | — | EP | disclosed |
| WO-2023213882-A1 | IRREVERSIBLE MUTEGFR INHIBITORS | BAYER AKTIENGESELLSCHAFT (DE) | 2023-11-09 | — | — | WO | disclosed |