Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 2/20 | 0.33 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.31 |
| ▸ | CSNK1D | P48730 | 2/20 | 0.31 |
| ▸ | CSNK1E | P49674 | 2/20 | 0.31 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.30 |
| ▸ | TOP2A | P11388 | 1/20 | 0.30 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30622347 | 0.90 | EGFR (0.35) | GHSR | |
| SCHEMBL26645120 | 0.90 | EGFR (0.35) | GHSR | |
| SCHEMBL26645143 | 0.90 | TMEM97 (0.35) | GHSR | |
| SCHEMBL30622814 | 0.88 | USP30 (0.32) | GHSR | |
| SCHEMBL26645478 | 0.86 | GHSR (0.33) | GHSR | |
| SCHEMBL26645626 | 0.83 | MAPK9 (0.40) | GHSRCSNK1DMAPK14 | |
| SCHEMBL26645220 | 0.80 | TMEM97 (0.33) | GHSR | |
| SCHEMBL30622329 | 0.80 | TMEM97 (0.33) | GHSR | |
| SCHEMBL26645621 | 0.79 | MAPK14 (0.40) | MAPK14 | |
| SCHEMBL26645097 | 0.79 | MAPK14 (0.40) | MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023213882-A1 | IRREVERSIBLE MUTEGFR INHIBITORS | BAYER AKTIENGESELLSCHAFT (DE) | 2023-11-09 | — | — | WO | disclosed |