Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 2/20 | 0.38 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.36 |
| ▸ | CKS1B | P61024 | 2/20 | 0.35 |
| ▸ | SKP1 | P63208 | 2/20 | 0.35 |
| ▸ | SKP2 | Q13309 | 2/20 | 0.35 |
| ▸ | NR1H2 | P55055 | 5/20 | 0.35 |
| ▸ | NR1H3 | Q13133 | 3/20 | 0.35 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.34 |
| ▸ | F2RL1 | P55085 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.33 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.33 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.33 |
| ▸ | RXRA | P19793 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26645385 | 0.92 | GPR119 (0.35) | RORCNR1H2USP30F2RL1C5AR1 | |
| SCHEMBL26645111 | 0.81 | NR1H2 (0.33) | RORCNR1H2 | |
| SCHEMBL26645440 | 0.76 | MAPK14 (0.40) | F2RL1 | |
| SCHEMBL26645047 | 0.76 | TGFBR1 (0.37) | — | |
| SCHEMBL26645024 | 0.72 | NR1H2 (0.36) | RORCNR1H2NR1H3F2RL1C5AR1 | |
| SCHEMBL26645301 | 0.70 | CSNK1D (0.44) | CKS1BSKP1SKP2NR1H2USP30 | |
| SCHEMBL26645539 | 0.70 | GPR119 (0.39) | RORCNR1H2USP30F2RL1 | |
| SCHEMBL24700154 | 0.69 | NAMPT (0.39) | RORCSCD5CKS1BSKP1SKP2 | |
| SCHEMBL292539 | 0.69 | NR1H2 (0.45) | RORCNR1H2NR1H3USP30ALDH1A1 | |
| SCHEMBL30622743 | 0.68 | USP30 (0.39) | USP30 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4519265-A1 | IRREVERSIBLE MUTEGFR INHIBITORS | Bayer Aktiengesellschaft (DE) | 2025-03-12 | — | — | EP | disclosed |
| WO-2023213882-A1 | IRREVERSIBLE MUTEGFR INHIBITORS | BAYER AKTIENGESELLSCHAFT (DE) | 2023-11-09 | — | — | WO | disclosed |