Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 11/20 | 0.43 |
| ▸ | CSNK1D | P48730 | 2/20 | 0.37 |
| ▸ | CSNK1E | P49674 | 2/20 | 0.37 |
| ▸ | GBA1 | P04062 | 1/20 | 0.36 |
| ▸ | NAMPT | P43490 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26645301 | 0.84 | CSNK1D (0.44) | GPR119CSNK1DCSNK1EGBA1MAPK1 | |
| SCHEMBL30622787 | 0.82 | BTK (0.40) | GPR119MAPK1LMNANR1H2 | |
| SCHEMBL26645177 | 0.82 | BTK (0.40) | GPR119MAPK1LMNANR1H2 | |
| SCHEMBL26645007 | 0.81 | JAK1 (0.43) | CSNK1DMAPK1 | |
| SCHEMBL30623067 | 0.81 | JAK1 (0.43) | CSNK1DMAPK1 | |
| SCHEMBL30622918 | 0.79 | CDK9 (0.39) | GPR119CSNK1DCSNK1EMAPK1NR1H2 | |
| SCHEMBL26645508 | 0.79 | CDK9 (0.39) | GPR119CSNK1DCSNK1EMAPK1NR1H2 | |
| SCHEMBL26645146 | 0.77 | CSNK1D (0.39) | CSNK1DCSNK1ENR1H2 | |
| SCHEMBL17129177 | 0.74 | CSNK1D (0.51) | GPR119CSNK1DCSNK1EMAPK1NR1H2 | |
| SCHEMBL30622970 | 0.74 | CSNK1D (0.38) | GPR119CSNK1DCSNK1ENAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4519265-A1 | IRREVERSIBLE MUTEGFR INHIBITORS | Bayer Aktiengesellschaft (DE) | 2025-03-12 | — | — | EP | disclosed |
| WO-2023213882-A1 | IRREVERSIBLE MUTEGFR INHIBITORS | BAYER AKTIENGESELLSCHAFT (DE) | 2023-11-09 | — | — | WO | disclosed |