Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK1D | P48730 | 2/20 | 0.39 |
| ▸ | CSNK1E | P49674 | 2/20 | 0.39 |
| ▸ | TBK1 | Q9UHD2 | 6/20 | 0.39 |
| ▸ | WNT3A | P56704 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | CFTR | P13569 | 1/20 | 0.37 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.37 |
| ▸ | KIT | P10721 | 2/20 | 0.36 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.36 |
| ▸ | BUB1 | O43683 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CKS1B | P61024 | 1/20 | 0.36 |
| ▸ | SKP1 | P63208 | 1/20 | 0.36 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | SYK | P43405 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26645301 | 0.85 | CSNK1D (0.44) | CSNK1DCSNK1EUSP30NR1H2POLB | |
| SCHEMBL30623067 | 0.79 | JAK1 (0.43) | CSNK1DKIT | |
| SCHEMBL26645007 | 0.79 | JAK1 (0.43) | CSNK1DKIT | |
| SCHEMBL26645508 | 0.77 | CDK9 (0.39) | CSNK1DCSNK1EKITNR1H2 | |
| SCHEMBL30622787 | 0.77 | BTK (0.40) | KITNR1H2POLB | |
| SCHEMBL30622918 | 0.77 | CDK9 (0.39) | CSNK1DCSNK1EKITNR1H2 | |
| SCHEMBL26645177 | 0.77 | BTK (0.40) | KITNR1H2POLB | |
| SCHEMBL26645108 | 0.77 | GPR119 (0.43) | CSNK1DCSNK1ENR1H2 | |
| SCHEMBL26645020 | 0.76 | CSNK1E (0.45) | CSNK1DCSNK1E | |
| SCHEMBL30622893 | 0.76 | CSNK1E (0.41) | CSNK1DCSNK1E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4519265-A1 | IRREVERSIBLE MUTEGFR INHIBITORS | Bayer Aktiengesellschaft (DE) | 2025-03-12 | — | — | EP | disclosed |
| WO-2023213882-A1 | IRREVERSIBLE MUTEGFR INHIBITORS | BAYER AKTIENGESELLSCHAFT (DE) | 2023-11-09 | — | — | WO | disclosed |