Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 4/20 | 0.34 |
| ▸ | HTR1A | P08908 | 2/20 | 0.33 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.31 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.30 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.30 |
| ▸ | DRD2 | P14416 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22119526 | 0.71 | KIF18A (0.38) | FFAR4 | |
| SCHEMBL30748599 | 0.70 | CDC7 (0.44) | — | |
| SCHEMBL29578579 | 0.67 | MEN1 (0.40) | — | |
| SCHEMBL30600578 | 0.67 | KIF18A (0.41) | — | |
| SCHEMBL22964565 | 0.67 | MEN1 (0.40) | — | |
| SCHEMBL22148553 | 0.66 | HTR1A (0.38) | FFAR4HTR1AADRA1B | |
| SCHEMBL29371596 | 0.66 | HTR1A (0.38) | FFAR4HTR1AADRA1B | |
| SCHEMBL30600625 | 0.65 | NOTUM (0.40) | — | |
| SCHEMBL31316101 | 0.65 | HTR1A (0.31) | HTR1AADRA1B | |
| SCHEMBL30600612 | 0.65 | CYP11B1 (0.31) | CYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4524136-A1 | KINESIN KIF18A INHIBITOR AND USE THEREOF | Shanghai Apeiron Therapeutics Company Limited (CN) | 2025-03-19 | — | — | EP | disclosed |
| WO-2025036479-A1 | KINESIN KIF18A INHIBITOR AND USE THEREOF | 上海湃隆生物科技有限公司 | 2025-02-20 | — | — | WO | disclosed |
| CN-119156382-A | Kinesin KIF18A inhibitor and application thereof | 上海湃隆生物科技有限公司 | 2024-12-17 | — | — | CN | disclosed |
| WO-2023217232-A1 | KINESIN KIF18A INHIBITOR AND USE THEREOF | 上海湃隆生物科技有限公司 | 2023-11-16 | — | — | WO | disclosed |