SCHEMBL266477

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL266478	1.00	MAPT (0.54)	MAPTALDH1A1MEN1KMT2APOLB
	SCHEMBL266583	0.89	PKM (0.62)	MAPTALDH1A1MEN1KMT2APOLB
	SCHEMBL266582	0.89	PKM (0.62)	MAPTALDH1A1MEN1KMT2APOLB
	SCHEMBL268756	0.89	KMT2A (0.51)	MAPTALDH1A1MEN1KMT2APOLB
	SCHEMBL267181	0.89	KMT2A (0.56)	MAPTALDH1A1MEN1KMT2APOLB
	SCHEMBL267182	0.89	KMT2A (0.56)	MAPTALDH1A1MEN1KMT2APOLB
	SCHEMBL268755	0.89	KMT2A (0.51)	MAPTALDH1A1MEN1KMT2APOLB
	SCHEMBL267496	0.82	RAB9A (0.61)	MAPTMEN1KMT2AL3MBTL1PKM
	SCHEMBL267497	0.82	RAB9A (0.61)	MAPTMEN1KMT2AL3MBTL1PKM
	Hydrochloric Acid SCHEMBL265645	0.82	RAB9A (0.60)	MAPTMEN1KMT2APOLBL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.