Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.45 |
| ▸ | DRD3 | P35462 | 1/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.44 |
| ▸ | AADAT | Q8N5Z0 | 2/20 | 0.36 |
| ▸ | KDM1A | O60341 | 6/20 | 0.35 |
| ▸ | KDM1B | Q8NB78 | 2/20 | 0.35 |
| ▸ | FYN | P06241 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | NOS3 | P29474 | 1/20 | 0.30 |
| ▸ | NOS2 | P35228 | 1/20 | 0.30 |
| ▸ | MAOA | P21397 | 1/20 | 0.30 |
| ▸ | MAOB | P27338 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11348400 | 0.77 | DRD2 (0.46) | DRD2DRD3ADRA1AFYN | |
| SCHEMBL1239050 | 0.77 | DRD2 (0.70) | DRD2DRD3AADAT | |
| SCHEMBL11362964 | 0.74 | HTR2C (0.44) | DRD2DRD3ADRA1AAADATFYN | |
| SCHEMBL29181797 | 0.74 | DRD2 (0.43) | DRD2DRD3ADRA1AKDM1AKDM1B | |
| SCHEMBL23261947 | 0.72 | DRD2 (0.38) | DRD2DRD3MAOA | |
| SCHEMBL24095330 | 0.69 | FYN (0.38) | DRD2DRD3ADRA1AAADATKDM1A | |
| SCHEMBL23857289 | 0.69 | ADRA1A (0.34) | ADRA1A | |
| SCHEMBL29605223 | 0.69 | ADRA1A (0.52) | ADRA1AAADATFYNMAOAMAOB | |
| SCHEMBL4819933 | 0.69 | ADRA1A (0.46) | ADRA1AFYN | |
| SCHEMBL8689448 | 0.69 | ADRA1A (0.52) | ADRA1AAADATFYNMAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4522596-A1 | DIHYDROINDENE DERIVATIVES AS MALT1 INHIBITORS | C4X Discovery Limited (GB) | 2025-03-19 | — | — | EP | disclosed |
| CN-119497712-A | Indane derivatives as MALT1 inhibitors | 希四克斯探索有限公司 | 2025-02-21 | — | — | CN | disclosed |
| WO-2023218203-A1 | DIHYDROINDENE DERIVATIVES AS MALT1 INHIBITORS | C4X DISCOVERY LIMITED (GB) | 2023-11-16 | — | — | WO | disclosed |