Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 3/20 | 0.46 |
| ▸ | FYN | P06241 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 1/20 | 0.32 |
| ▸ | PLAU | P00749 | 1/20 | 0.31 |
| ▸ | NR2E1 | Q9Y466 | 1/20 | 0.31 |
| ▸ | LGMN | Q99538 | 1/20 | 0.30 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA7 | P43166 | 1/20 | 0.30 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4825590 | 0.83 | ADRA1A (0.50) | ADRA1APLAUNR2E1 | |
| SCHEMBL21447755 | 0.76 | DRD2 (0.47) | ADRA1AFYNPLAU | |
| SCHEMBL4826835 | 0.74 | PARP1 (0.35) | PARP1 | |
| SCHEMBL4825996 | 0.74 | PARP1 (0.39) | ADRA1APARP1 | |
| Hydrochloric Acid SCHEMBL4825596 | 0.72 | PARP1 (0.34) | PARP1 | |
| SCHEMBL8689448 | 0.71 | ADRA1A (0.52) | ADRA1AFYNPLAU | |
| SCHEMBL4823313 | 0.70 | BPTF (0.32) | PARP1 | |
| SCHEMBL5157368 | 0.67 | CD44 (0.36) | PARP1 | |
| SCHEMBL21436516 | 0.67 | AKR1C3 (0.42) | PARP1CA12CA1CA2CA7 | |
| SCHEMBL4825528 | 0.67 | PARP1 (0.33) | PARP1LGMN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7396369-B2 | 2,3-disubstituted primary para-phenylenediamines and process for oxidation dyeing of keratin fibers | L'OREAL S.A. (FR) | 2008-07-08 | — | — | US | claimed |
| US-20070011823-A1 | Novel 2,3-disubstituted primary para-phenylenediamines and process for oxidation dyeing of keratin fibers | L'OREAL S.A. (FR) | 2007-01-18 | — | — | US | claimed |
| EP-1739073-A1 | New primary 2,3-disubstituted para-phenylendiamins and their use as oxidative colouring of keratinic fibers | L'Oréal (FR) | 2007-01-03 | — | — | EP | claimed |
| US-7396369-B2 | 2,3-disubstituted primary para-phenylenediamines and process for oxidation dyeing of keratin fibers | L'OREAL S.A. (FR) | 2008-07-08 | — | — | US | disclosed |
| US-7396369-B2 | 2,3-disubstituted primary para-phenylenediamines and process for oxidation dyeing of keratin fibers | L'OREAL S.A. (FR) | 2008-07-08 | — | — | US | disclosed |
| US-7396369-B2 | 2,3-disubstituted primary para-phenylenediamines and process for oxidation dyeing of keratin fibers | L'OREAL S.A. (FR) | 2008-07-08 | — | — | US | disclosed |
| US-20070011823-A1 | Novel 2,3-disubstituted primary para-phenylenediamines and process for oxidation dyeing of keratin fibers | L'OREAL S.A. (FR) | 2007-01-18 | — | — | US | disclosed |
| US-20070011823-A1 | Novel 2,3-disubstituted primary para-phenylenediamines and process for oxidation dyeing of keratin fibers | L'OREAL S.A. (FR) | 2007-01-18 | — | — | US | disclosed |
| US-20070011823-A1 | Novel 2,3-disubstituted primary para-phenylenediamines and process for oxidation dyeing of keratin fibers | L'OREAL S.A. (FR) | 2007-01-18 | — | — | US | disclosed |
| EP-1739073-A1 | New primary 2,3-disubstituted para-phenylendiamins and their use as oxidative colouring of keratinic fibers | L'Oréal (FR) | 2007-01-03 | — | — | EP | disclosed |
| EP-1739073-A1 | New primary 2,3-disubstituted para-phenylendiamins and their use as oxidative colouring of keratinic fibers | L'Oréal (FR) | 2007-01-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070011823-A1 | Novel 2,3-disubstituted primary para-phenylenediamines and process for oxidation dyeing of keratin fibers | KRT18, VIM, CDC73 | ADRA1A 2121/4885FYN 2690/4885PARP1 560/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.