SCHEMBL8689448

SCHEMBL8689448

Cc1ccc(C)c2c1CC(N)C2

nearest known ligand 0.52

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ADRA1A P35348 3/20 0.52
AADAT Q8N5Z0 2/20 0.37
FYN P06241 1/20 0.35
ACHE P22303 1/20 0.34
MAOA P21397 3/20 0.33
MAOB P27338 2/20 0.33
ALDH1A1 P00352 1/20 0.32
POLL Q9UGP5 1/20 0.32
PLAU P00749 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31278528 0.79 DRD2 (0.46) ADRA1AAADATFYNACHEPLAU
SCHEMBL8692015 0.79 ADRA1A (0.41) ADRA1AFYNPLAU
SCHEMBL2079549 0.79 DRD2 (0.46) ADRA1AAADATFYNACHEPLAU
SCHEMBL23856867 0.76 ADRA1A (0.38) ADRA1A
SCHEMBL7156116 0.73 ACHE (0.40) AADATACHEMAOAMAOBALDH1A1
SCHEMBL20608873 0.71 MAOA (0.39) ADRA1AMAOAMAOB
SCHEMBL4819933 0.71 ADRA1A (0.46) ADRA1AFYNPLAU
SCHEMBL14035780 0.71 ACHE (0.34) ACHEMAOAMAOBALDH1A1POLL
Bromide SCHEMBL20554731 0.70 MAOA (0.38) MAOAMAOB
SCHEMBL8689227 0.69 FYN (0.40) ADRA1AAADATFYNALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112500301-B Regulator for longitudinal behavior 以西结·戈兰 2024-02-13 CN claimed
US-20250288541-A1 BINGE BEHAVIOR REGULATORS CLEARMIND LABS CORP. (CA) 2025-09-18 US disclosed
US-12357590-B2 Binge behavior regulators Clearmind Medicine Inc. (CA) 2025-07-15 US disclosed
US-12350242-B2 Binge behavior regulators Clearmind Medicine Inc. (CA) 2025-07-08 US disclosed
EP-4522596-A1 DIHYDROINDENE DERIVATIVES AS MALT1 INHIBITORS C4X Discovery Limited (GB) 2025-03-19 EP disclosed
US-12064402-B2 Binge behavior regulators Clearmind Medicine Inc. (CA) 2024-08-20 US disclosed
WO-2024062395-A1 USE OF 5-METHOXY-2-AMINOINDAN (\"MEAI\") IN METHODS FOR TREATING METABOLIC SYNDROME Clearmind Medicine Inc. (IL) 2024-03-28 WO disclosed
CN-112500301-B Regulator for longitudinal behavior 以西结·戈兰 2024-02-13 CN disclosed
WO-2023218203-A1 DIHYDROINDENE DERIVATIVES AS MALT1 INHIBITORS C4X DISCOVERY LIMITED (GB) 2023-11-16 WO disclosed
US-20230092839-A1 ALCOHOLIC BEVERAGE SUBSTITUTES Clearmind Medicine Inc. (CA) 2023-03-23 US disclosed
US-10137096-B2 Binge behavior regulators CLEARMIND LABS CORP. (CA) 2018-11-27 US disclosed
US-20180085326-A1 BINGE BEHAVIOR REGULATORS CLEARMIND LABS CORP. (CA) 2018-03-29 US disclosed
US-20170360067-A1 ALCOHOLIC BEVERAGE SUBSTITUTES CLEARMIND LABS CORP. (CA) 2017-12-21 US disclosed
CN-107406370-A Alcoholic beverage substitute 以西结·戈兰 2017-11-28 CN disclosed
CN-107406369-A Relaxant behavior modulators 以西结·戈兰 2017-11-28 CN disclosed
EP-3230256-A1 ALCOHOLIC BEVERAGE SUBSTITUTES Golan, Ezekiel (CA) 2017-10-18 EP disclosed
WO-2016092547-A1 ALCOHOLIC BEVERAGE SUBSTITUTES GOLAN EZEKIEL (IL) 2016-06-16 WO disclosed
US-5708018-A 2-aminoindans as selective dopamine D3 ligands PHARMACIA & UPJOHN COMPANY (US) 1998-01-13 US disclosed
EP-0712387-A1 2-AMINOINDANS AS SELECTIVE DOPAMINE D3 LIGANDS PHARMACIA & UPJOHN COMPANY (US) 1996-05-22 EP disclosed
WO-1995004713-A1 2-AMINOINDANS AS SELECTIVE DOPAMINE D3 LIGANDS THE UPJOHN COMPANY (US) 1995-02-16 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250288541-A1 BINGE BEHAVIOR REGULATORS GABRB3, GABRB2, GABRB1 ADRA1A 1345/4885AADAT 508/4885FYN 4855/4885
US-20180085326-A1 BINGE BEHAVIOR REGULATORS GABRB3, GABRB2, GABRB1 ADRA1A 1345/4885AADAT 508/4885FYN 4855/4885
US-20230092839-A1 ALCOHOLIC BEVERAGE SUBSTITUTES ADH1A, ADH5, ADH1C ADRA1A 1477/4885AADAT 11/4885FYN 3559/4885
US-12350242-B2 Binge behavior regulators GABRB3, GABRB2, GABRB1 ADRA1A 1345/4885AADAT 508/4885FYN 4855/4885
US-10137096-B2 Binge behavior regulators GABRB3, GABRB2, GABRB1 ADRA1A 1345/4885AADAT 508/4885FYN 4855/4885
US-12064402-B2 Binge behavior regulators GABRB3, GABRB2, GABRB1 ADRA1A 1345/4885AADAT 508/4885FYN 4855/4885
US-12357590-B2 Binge behavior regulators GABRB3, GABRB2, GABRB1 ADRA1A 1345/4885AADAT 508/4885FYN 4855/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.