Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 2/20 | 0.36 |
| ▸ | NOS1 | P29475 | 2/20 | 0.36 |
| ▸ | NOS2 | P35228 | 2/20 | 0.36 |
| ▸ | MBOAT4 | Q96T53 | 2/20 | 0.35 |
| ▸ | FFAR2 | O15552 | 5/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.33 |
| ▸ | MTOR | P42345 | 1/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.32 |
| ▸ | SCN10A | Q9Y5Y9 | 2/20 | 0.32 |
| ▸ | CNR2 | P34972 | 2/20 | 0.32 |
| ▸ | WHR1 | P49842 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26650584 | 1.00 | NOS3 (0.36) | NOS3NOS1NOS2MBOAT4FFAR2 | |
| SCHEMBL26650968 | 0.84 | NOS3 (0.36) | NOS3NOS1NOS2MBOAT4FFAR2 | |
| SCHEMBL26650429 | 0.84 | NOS3 (0.41) | NOS3NOS1NOS2MBOAT4FFAR2 | |
| SCHEMBL26650701 | 0.83 | SCN10A (0.41) | NOS3NOS1NOS2FFAR2PIK3CA | |
| SCHEMBL26650487 | 0.78 | GRM4 (0.43) | NOS3NOS1NOS2FFAR2PIK3CA | |
| SCHEMBL29074142 | 0.74 | MBOAT4 (0.49) | NOS3NOS1NOS2MBOAT4FFAR2 | |
| SCHEMBL30527887 | 0.74 | MBOAT4 (0.49) | NOS3NOS1NOS2MBOAT4FFAR2 | |
| SCHEMBL26650606 | 0.73 | SCN10A (0.39) | NOS3NOS1NOS2FFAR2PIK3CA | |
| SCHEMBL30748557 | 0.73 | SCN10A (0.39) | NOS3NOS1NOS2FFAR2PIK3CA | |
| SCHEMBL31485331 | 0.71 | GSK3B (0.39) | SCN10AWHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119212988-A | Kinesin KIF18A inhibitor and application thereof | 上海湃隆生物科技有限公司 | 2024-12-27 | — | — | CN | disclosed |
| WO-2023217230-A1 | KINESIN KIF18A INHIBITOR AND USE THEREOF | 上海湃隆生物科技有限公司 | 2023-11-16 | — | — | WO | disclosed |