Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCGR | P47871 | 12/20 | 0.40 |
| ▸ | GIPR | P48546 | 10/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 3/20 | 0.33 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | PPARD | Q03181 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2664963 | 0.98 | GCGR (0.41) | GCGRGIPRMAPK14KMT2APPARD | |
| SCHEMBL2665079 | 0.92 | GCGR (0.43) | GCGRGIPRMAPK14OPRM1OPRD1 | |
| SCHEMBL9071438 | 0.90 | GCGR (0.45) | GCGRGIPRMAPK14OPRM1OPRD1 | |
| SCHEMBL9071416 | 0.87 | GCGR (0.40) | GCGRGIPRMAPK14NPC1RAB9A | |
| SCHEMBL2665135 | 0.85 | GCGR (0.47) | GCGRGIPRMAPK14OPRM1OPRD1 | |
| SCHEMBL9071414 | 0.85 | GCGR (0.42) | GCGRGIPRMAPK14NPC1RAB9A | |
| SCHEMBL2665050 | 0.84 | GCGR (0.55) | GCGRGIPRPPARD | |
| SCHEMBL2665137 | 0.84 | GCGR (0.47) | GCGRGIPRMAPK14 | |
| SCHEMBL2665047 | 0.84 | GCGR (0.45) | GCGRGIPRMAPK14 | |
| SCHEMBL2665080 | 0.82 | GCGR (0.44) | GCGRGIPRMAPK14OPRM1OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003048109-A1 | NOVEL GLUCAGON ANTAGONISTS | NOVO NORDISK A/S (DK) | 2003-06-12 | — | — | WO | disclosed |