SCHEMBL26650575

SCHEMBL26650575

Cc1ccc2sc3cc(C(N)=O)c(CC(C)C)c(CC(C)C)c3c(=O)c2c1

nearest known ligand 0.38

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
POLB P06746 6/20 0.38
ALDH1A1 P00352 2/20 0.38
KDM4E B2RXH2 1/20 0.38
HPGD P15428 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.35
MAPT P10636 2/20 0.33
MEN1 O00255 1/20 0.33
GAA P10253 1/20 0.33
KMT2A Q03164 1/20 0.33
MAOA P21397 1/20 0.32
MAOB P27338 1/20 0.32
IKBKB O14920 2/20 0.32
DPP4 P27487 1/20 0.31
ICAM1 P05362 3/20 0.31
SELE P16581 3/20 0.31
VCAM1 P19320 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Formamide SCHEMBL27913100 0.76 ALDH1A1 (0.32) POLBALDH1A1KDM4EHPGDMAPT
SCHEMBL1609870 0.68 KDM4E (0.51) POLBALDH1A1KDM4EHPGDL3MBTL1
SCHEMBL28806848 0.68 HPGD (0.36) POLBALDH1A1KDM4EHPGDMAPT
SCHEMBL4543083 0.67 HPGD (0.42) POLBALDH1A1KDM4EHPGDMAPT
SCHEMBL4537030 0.67 ALDH1A1 (0.51) POLBALDH1A1KDM4EHPGDL3MBTL1
SCHEMBL4542795 0.65 ALDH1A1 (0.49) POLBALDH1A1KDM4EHPGDL3MBTL1
SCHEMBL27913094 0.64 KDM4E (0.46) POLBALDH1A1KDM4EHPGDL3MBTL1
SCHEMBL10805493 0.64 PNMT (0.39) POLBALDH1A1KDM4EHPGDL3MBTL1
SCHEMBL5803208 0.64 POLB (0.49) POLBALDH1A1HPGDL3MBTL1MEN1
SCHEMBL4539088 0.64 MLYCD (0.40) POLBALDH1A1KDM4EHPGDMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023218168-A1 LOW GLOSS INKJET INKS SUN CHEMICAL CORPORATION (US) 2023-11-16 WO claimed