Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | POLA1 | P09884 | 1/20 | 0.49 |
| ▸ | DGKA | P23743 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | CES2 | O00748 | 1/20 | 0.47 |
| ▸ | GMNN | O75496 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26650816 | 1.00 | POLB (0.49) | POLBPOLA1DGKATSHRMAPT | |
| SCHEMBL26650847 | 1.00 | POLB (0.49) | POLBPOLA1DGKATSHRMAPT | |
| SCHEMBL15593806 | 0.93 | TSHR (0.52) | POLBPOLA1DGKATSHRMAPT | |
| SCHEMBL29365230 | 0.93 | TSHR (0.52) | POLBPOLA1DGKATSHRMAPT | |
| SCHEMBL9402917 | 0.89 | TSHR (0.52) | POLBPOLA1DGKATSHRMAPT | |
| SCHEMBL26650784 | 0.87 | TSHR (0.50) | POLBPOLA1DGKATSHRMAPT | |
| SCHEMBL11639760 | 0.85 | CES2 (0.50) | POLBPOLA1DGKATSHRMAPT | |
| SCHEMBL10503461 | 0.85 | CES2 (0.50) | POLBPOLA1DGKATSHRMAPT | |
| SCHEMBL11639935 | 0.85 | CES2 (0.50) | POLBPOLA1DGKATSHRMAPT | |
| SCHEMBL8895243 | 0.85 | CES2 (0.50) | POLBPOLA1DGKATSHRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260115139-A1 | Amino Acid-Containing Ionizable Lipids for the Delivery of Therapeutic Agents | NANOVATION THERAPEUTICS INC. (CA) | 2026-04-30 | — | — | US | disclosed |
| US-20250304547-A1 | Sulfur-Containing Lipids | NANOVATION THERAPEUTICS INC. (CA) | 2025-10-02 | — | — | US | disclosed |
| EP-4594293-A1 | AMINO ACID-CONTAINING IONIZABLE LIPIDS FOR THE DELIVERY OF THERAPEUTIC AGENTS | Nanovation Therapeutics Inc. (CA) | 2025-08-06 | — | — | EP | disclosed |
| US-20240287015-A1 | Method for Producing an Ionizable Lipid | NANOVATION THERAPEUTICS INC. (CA) | 2024-08-29 | — | — | US | disclosed |
| WO-2024065043-A1 | AMINO ACID-CONTAINING IONIZABLE LIPIDS FOR THE DELIVERY OF THERAPEUTIC AGENTS | NANOVATION THERAPEUTICS INC. (CA) | 2024-04-04 | — | — | WO | disclosed |
| WO-2023215989-A1 | SULFUR-CONTAINING LIPIDS | NANOVATION THERAPEUTICS INC. (CA) | 2023-11-16 | — | — | WO | disclosed |
| WO-2023215989-A1 | SULFUR-CONTAINING LIPIDS | NANOVATION THERAPEUTICS INC. (CA) | 2023-11-16 | — | — | WO | disclosed |
| WO-2022246555-A1 | METHOD FOR PRODUCING AN IONIZABLE LIPID | NANOVATION THERAPEUTICS INC. (CA) | 2022-12-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260115139-A1 | Amino Acid-Containing Ionizable Lipids for the Delivery of Therapeutic Agents | SLC43A1, SLC7A1, SLC7A5 | POLB 364/4885POLA1 267/4885DGKA 1248/4885 |
| US-20240287015-A1 | Method for Producing an Ionizable Lipid | CEL, FASN, COASY | POLB 2233/4885POLA1 1402/4885DGKA 334/4885 |
| US-20250304547-A1 | Sulfur-Containing Lipids | FABP1, SLC10A1, MPST | POLB 1586/4885POLA1 1137/4885DGKA 1184/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.