Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCGR | P47871 | 7/20 | 0.43 |
| ▸ | GIPR | P48546 | 5/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.35 |
| ▸ | KCNK2 | O95069 | 5/20 | 0.35 |
| ▸ | KCNK10 | P57789 | 4/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.34 |
| ▸ | NAMPT | P43490 | 1/20 | 0.34 |
| ▸ | PPARD | Q03181 | 1/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GLP1R | P43220 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9071438 | 0.98 | GCGR (0.45) | GCGRGIPREPHX2NR1H4OPRM1 | |
| SCHEMBL2664962 | 0.92 | GCGR (0.40) | GCGRGIPROPRM1OPRD1MAPK14 | |
| SCHEMBL2664963 | 0.90 | GCGR (0.41) | GCGRGIPRMAPK14PPARDGLP1R | |
| SCHEMBL2665228 | 0.86 | GCGR (0.44) | GCGRGIPREPHX2NR1H4KCNK2 | |
| SCHEMBL2665084 | 0.86 | GCGR (0.42) | GCGRGIPROPRM1OPRD1MAPK14 | |
| SCHEMBL2665080 | 0.85 | GCGR (0.44) | GCGRGIPROPRM1OPRD1MAPK14 | |
| SCHEMBL9071435 | 0.84 | GCGR (0.53) | GCGRGIPREPHX2NR1H4OPRM1 | |
| SCHEMBL2665086 | 0.84 | GCGR (0.48) | GCGRGIPROPRM1OPRD1MAPK14 | |
| SCHEMBL2665091 | 0.84 | GCGR (0.42) | GCGRGIPREPHX2NR1H4OPRM1 | |
| SCHEMBL9071390 | 0.83 | GCGR (0.42) | GCGRGIPREPHX2NR1H4KCNK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003048109-A1 | NOVEL GLUCAGON ANTAGONISTS | NOVO NORDISK A/S (DK) | 2003-06-12 | — | — | WO | disclosed |