Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCGR | P47871 | 9/20 | 0.42 |
| ▸ | GIPR | P48546 | 6/20 | 0.40 |
| ▸ | DHODH | Q02127 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.38 |
| ▸ | GLP1R | P43220 | 2/20 | 0.37 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2665084 | 0.98 | GCGR (0.42) | GCGRGIPRDHODHALDH1A1LMNA | |
| SCHEMBL2665086 | 0.87 | GCGR (0.48) | GCGRGIPRGLP1ROPRM1OPRD1 | |
| SCHEMBL2665080 | 0.86 | GCGR (0.44) | GCGRGIPRALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL9071436 | 0.86 | GCGR (0.43) | GCGRGIPRGLP1ROPRM1OPRD1 | |
| SCHEMBL9071435 | 0.86 | GCGR (0.53) | GCGRGIPRDHODHTRPV1NR1H4 | |
| SCHEMBL9071438 | 0.86 | GCGR (0.45) | GCGRGIPRGLP1RNR1H4EPHX2 | |
| SCHEMBL2665079 | 0.84 | GCGR (0.43) | GCGRGIPRALDH1A1TRPV1GLP1R | |
| SCHEMBL2665222 | 0.83 | KMT2A (0.41) | GCGRGIPRALDH1A1LMNAMAPT | |
| SCHEMBL9071502 | 0.83 | GCGR (0.51) | GCGRGIPRGLP1RNR1H4EPHX2 | |
| SCHEMBL2665128 | 0.82 | GCGR (0.56) | GCGRGIPRLMNAMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003048109-A1 | NOVEL GLUCAGON ANTAGONISTS | NOVO NORDISK A/S (DK) | 2003-06-12 | — | — | WO | disclosed |