Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCGR | P47871 | 8/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
| ▸ | GIPR | P48546 | 5/20 | 0.38 |
| ▸ | DHODH | Q02127 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | GLP1R | P43220 | 2/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2665091 | 0.98 | GCGR (0.42) | GCGROPRM1OPRD1GIPRDHODH | |
| SCHEMBL2665080 | 0.88 | GCGR (0.44) | GCGROPRM1OPRD1GIPRALDH1A1 | |
| SCHEMBL2665079 | 0.86 | GCGR (0.43) | GCGROPRM1OPRD1GIPRALDH1A1 | |
| SCHEMBL2665086 | 0.85 | GCGR (0.48) | GCGROPRM1OPRD1GIPRGLP1R | |
| SCHEMBL2665222 | 0.85 | KMT2A (0.41) | GCGRGIPRLMNAALDH1A1MAPT | |
| SCHEMBL9071436 | 0.84 | GCGR (0.43) | GCGROPRM1OPRD1GIPRGLP1R | |
| SCHEMBL9071438 | 0.84 | GCGR (0.45) | GCGROPRM1OPRD1GIPRGLP1R | |
| SCHEMBL9071435 | 0.84 | GCGR (0.53) | GCGROPRM1OPRD1GIPRDHODH | |
| SCHEMBL2665128 | 0.82 | GCGR (0.56) | GCGRGIPRLMNAMAPTSMN1; SMN2 | |
| SCHEMBL2665120 | 0.81 | GCGR (0.49) | GCGROPRM1OPRD1GIPRGLP1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003048109-A1 | NOVEL GLUCAGON ANTAGONISTS | NOVO NORDISK A/S (DK) | 2003-06-12 | — | — | WO | disclosed |