Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCGR | P47871 | 8/20 | 0.44 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.40 |
| ▸ | GIPR | P48546 | 5/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
| ▸ | GLP1R | P43220 | 2/20 | 0.36 |
| ▸ | TAOK3 | Q9H2K8 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2665084 | 0.88 | GCGR (0.42) | GCGRMAPK14GIPRRAB9ASMN1; SMN2 | |
| SCHEMBL2665091 | 0.86 | GCGR (0.42) | GCGRMAPK14GIPRSMN1; SMN2TP53 | |
| SCHEMBL9071436 | 0.85 | GCGR (0.43) | GCGRPRMT5MAPK14GIPROPRM1 | |
| SCHEMBL2665079 | 0.85 | GCGR (0.43) | GCGRMAPK14GIPROPRM1OPRD1 | |
| SCHEMBL2665223 | 0.85 | GCGR (0.43) | GCGRMAPK14GIPRHDAC6NPC1 | |
| SCHEMBL9071438 | 0.83 | GCGR (0.45) | GCGRMAPK14GIPROPRM1OPRD1 | |
| SCHEMBL9071435 | 0.83 | GCGR (0.53) | GCGRMAPK14GIPROPRM1OPRD1 | |
| SCHEMBL2665224 | 0.83 | GCGR (0.43) | GCGRMAPK14GIPRHDAC6NPC1 | |
| SCHEMBL2665086 | 0.83 | GCGR (0.48) | GCGRMAPK14GIPROPRM1OPRD1 | |
| SCHEMBL9071501 | 0.82 | GCGR (0.57) | GCGRPRMT5GIPRGLP1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003048109-A1 | NOVEL GLUCAGON ANTAGONISTS | NOVO NORDISK A/S (DK) | 2003-06-12 | — | — | WO | disclosed |