Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCGR | P47871 | 6/20 | 0.43 |
| ▸ | GIPR | P48546 | 5/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2665224 | 0.98 | GCGR (0.43) | GCGRGIPRNPC1RAB9AMAPK14 | |
| SCHEMBL2665222 | 0.87 | KMT2A (0.41) | GCGRGIPRNPC1RAB9AKMT2A | |
| SCHEMBL2665080 | 0.85 | GCGR (0.44) | GCGRGIPRNPC1RAB9AMAPK14 | |
| SCHEMBL2665226 | 0.84 | FABP4 (0.43) | GCGRGIPRNPC1RAB9ANFKB1 | |
| SCHEMBL2665228 | 0.84 | GCGR (0.44) | GCGRGIPRNPC1RAB9AMAPK14 | |
| SCHEMBL2655953 | 0.84 | GCGR (0.52) | GCGRGIPR | |
| SCHEMBL2655948 | 0.84 | GCGR (0.52) | GCGRGIPR | |
| SCHEMBL2665225 | 0.82 | GCGR (0.52) | GCGRGIPR | |
| SCHEMBL2665164 | 0.82 | GCGR (0.47) | GCGRGIPRGCG | |
| SCHEMBL9071388 | 0.82 | GCGR (0.53) | GCGRGIPRNPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003048109-A1 | NOVEL GLUCAGON ANTAGONISTS | NOVO NORDISK A/S (DK) | 2003-06-12 | — | — | WO | disclosed |