SCHEMBL26652142

SCHEMBL26652142

B[C@@H]1OC(COC)[C@@H](OC)[C@H]1OCCC

nearest known ligand 0.38

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ FGF1 P05230 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22317546 0.88 — —
SCHEMBL21123603 0.88 — —
SCHEMBL14537230 0.88 — —
SCHEMBL14624334 0.88 — —
SCHEMBL26253255 0.88 — —
SCHEMBL14295972 0.88 — —
SCHEMBL14622977 0.86 — —
SCHEMBL10001262 0.84 FGF1 (0.33) FGF1
SCHEMBL13222901 0.84 FGF1 (0.33) FGF1
SCHEMBL10310995 0.84 FGF1 (0.33) FGF1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11801311-B2 Inhibiting or downregulating glycogen synthase by creating premature stop codons using antisense oligonucleotides GENZYME CORPORATION (US) 2023-10-31 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11801311-B2 Inhibiting or downregulating glycogen synthase by creating premature stop codons using antisense oligonucleotides GYS1, PYGM, TNNC1 FGF1 4720/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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