Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.47 |
| ▸ | USP2 | O75604 | 2/20 | 0.47 |
| ▸ | NPC1L1 | Q9UHC9 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.46 |
| ▸ | PGR | P06401 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | AR | P10275 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26653624 | 1.00 | ALDH1A1 (0.47) | ALDH1A1LMNAMAPTALOX15USP2 | |
| SCHEMBL26653373 | 0.88 | NPC1L1 (0.49) | ALDH1A1LMNAMAPTALOX15USP2 | |
| SCHEMBL26653376 | 0.88 | NPC1L1 (0.49) | ALDH1A1LMNAMAPTALOX15USP2 | |
| SCHEMBL29486954 | 0.88 | NPC1L1 (0.49) | ALDH1A1LMNAMAPTALOX15USP2 | |
| SCHEMBL29486944 | 0.87 | LMNA (0.63) | ALDH1A1LMNAMAPTALOX15USP2 | |
| SCHEMBL11232551 | 0.87 | LMNA (0.63) | ALDH1A1LMNAMAPTALOX15USP2 | |
| SCHEMBL11232557 | 0.87 | LMNA (0.63) | ALDH1A1LMNAMAPTALOX15USP2 | |
| SCHEMBL26653679 | 0.87 | LMNA (0.63) | ALDH1A1LMNAMAPTALOX15USP2 | |
| SCHEMBL29486942 | 0.87 | LMNA (0.63) | ALDH1A1LMNAMAPTALOX15USP2 | |
| SCHEMBL26653683 | 0.87 | LMNA (0.63) | ALDH1A1LMNAMAPTALOX15USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230365616-A1 | CHOLESTANE DERIVATIVES, PREPARATIONS CONTAINING THESE DERIVATIVES AND USE THEREOF | UNIVERZITA PALACKEHO V OLOMOUCI (CZ) | 2023-11-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230365616-A1 | CHOLESTANE DERIVATIVES, PREPARATIONS CONTAINING THESE DERIVATIVES AND USE THEREOF | BAD, CYP27A1, NPC1L1 | ALDH1A1 3863/4885LMNA 1058/4885MAPT 214/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.