SCHEMBL26654656

SCHEMBL26654656

CN(C)C(C(=O)O)C1CCc2ccccc2C1

nearest known ligand 0.44

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
MTNR1A P48039 4/20 0.44
MTNR1B P49286 4/20 0.44
NPY5R Q15761 1/20 0.41
PLAU P00749 1/20 0.39
HTR1A P08908 1/20 0.38
GHSR Q92847 1/20 0.38
ANPEP P15144 1/20 0.37
PRMT5 O14744 1/20 0.37
AKR1C3 P42330 1/20 0.36
GRM7 Q14831 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2480890 0.80 MTNR1A (0.47) MTNR1AMTNR1BNPY5RPLAUANPEP
SCHEMBL11472821 0.78 MTNR1A (0.45) MTNR1AMTNR1BPLAUANPEPPRMT5
SCHEMBL16593842 0.78 PLAU (0.43) MTNR1AMTNR1BNPY5RPLAUHTR1A
SCHEMBL3611898 0.76 PLAU (0.46) MTNR1AMTNR1BPLAUANPEPAKR1C3
SCHEMBL17995302 0.76 MTNR1A (0.48) MTNR1AMTNR1BNPY5RPLAUGHSR
SCHEMBL7301985 0.76 MTNR1A (0.44) MTNR1AMTNR1BNPY5RPLAUANPEP
Hydrochloric Acid SCHEMBL7706077 0.74 MTNR1A (0.39) MTNR1AMTNR1BNPY5RHTR1AGHSR
SCHEMBL2597095 0.72 MTNR1A (0.46) MTNR1AMTNR1BPLAUANPEPGRM7
SCHEMBL19688497 0.72 PLAU (0.47) MTNR1AMTNR1BPLAUHTR1AANPEP
SCHEMBL10557222 0.71 PLAU (0.50) MTNR1AMTNR1BPLAUHTR1AANPEP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023219548-A1 SELECTIVE DOPAMINE INCREASE SOBRERA PHARMA AB (SE) 2023-11-16 WO disclosed