Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | TDO2 | P48775 | 1/20 | 0.39 |
| ▸ | CA4 | P22748 | 2/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | DPP4 | P27487 | 2/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6359298 | 1.00 | KMT2A (0.41) | KMT2AEPHX1THRBIDO1TDO2 | |
| SCHEMBL26689 | 0.89 | KMT2A (0.44) | KMT2AEPHX1THRBIDO1TDO2 | |
| SCHEMBL12261012 | 0.88 | THRB (0.40) | KMT2AEPHX1THRBIDO1TDO2 | |
| Iodide SCHEMBL27504755 | 0.86 | KMT2A (0.43) | KMT2AEPHX1THRBIDO1TDO2 | |
| Lithium SCHEMBL30301644 | 0.86 | KMT2A (0.43) | KMT2AEPHX1THRBIDO1TDO2 | |
| SCHEMBL28261380 | 0.84 | KMT2A (0.39) | KMT2AEPHX1THRBTSHRMEN1 | |
| SCHEMBL10607695 | 0.84 | KMT2A (0.41) | KMT2AEPHX1THRBIDO1TDO2 | |
| SCHEMBL18688775 | 0.81 | TRPA1 (0.40) | KMT2ATSHRMEN1ATML3MBTL1 | |
| SCHEMBL14660344 | 0.80 | KMT2A (0.43) | KMT2AEPHX1THRBIDO1TDO2 | |
| SCHEMBL18940434 | 0.80 | KMT2A (0.39) | KMT2AEPHX1THRBIDO1TDO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 649 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240141362-A1 | MODIFIED OLIGONUCLEOTIDES WITH INCREASED STABILITY | UNIV MASSACHUSETTS (US) | 2024-05-02 | — | — | US | claimed |
| US-11820985-B2 | Modified oligonucleotides with increased stability | UNIVERSITY OF MASSACHUSETTS (US) | 2023-11-21 | — | — | US | claimed |
| EP-4203940-A1 | METHODS TO PRODUCE VERY LONG CHAIN FATTY ACIDS (VLCFA) | The United States Of America, As Represented By The Secretary, Department of Health and Human Services (US) | 2023-07-05 | — | — | EP | claimed |
| EP-3946369-A2 | MODIFIED OLIGONUCLEOTIDES WITH INCREASED STABILITY | University Of Massachusetts (US) | 2022-02-09 | — | — | EP | claimed |
| CN-112175265-A | Modified color master batch and preparation method thereof | 方少山 | 2021-01-05 | — | — | CN | claimed |
| US-20200385740-A1 | MODIFIED OLIGONUCLEOTIDES WITH INCREASED STABILITY | UNIVERSITY OF MASSACHUSETTS | 2020-12-10 | — | — | US | claimed |
| EP-3746509-A1 | BUGPHOBIC AND ICEPHOBIC COMPOSITIONS WITH FLUID ADDITIVES | HRL Laboratories, LLC (US) | 2020-12-09 | — | — | EP | claimed |
| WO-2020198509-A2 | MODIFIED OLIGONUCLEOTIDES WITH INCREASED STABILITY | UNIVERSITY OF MASSACHUSETTS (US) | 2020-10-01 | — | — | WO | claimed |
| CN-106573904-B | Method for generating beraprost and its derivative | 朗格生物技术公共公益股份有限公司 | 2019-11-08 | — | — | CN | claimed |
| CN-106458923-B | Heterocyclic compound | 株式会社大熊制药 | 2019-09-10 | — | — | CN | claimed |
| CN-100355772-C | Steroid compound with 5-alpha reductase active and preparation process thereof | UNIV TIANJIN (CN) | 2007-12-19 | — | — | CN | claimed |
| WO-2007088186-A1 | NOVEL SILANE COMPOUNDS AND USE THEREOF IN ORDER TO FUNCTIONALISE SOLID MEDIA AND IMMOBILISE BIOLOGICAL MOLECULES ON SAID MEDIA | COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) | 2007-08-09 | — | — | WO | claimed |
| WO-2006127893-A2 | PROCESSES FOR PRODUCTION OF 4-(BIPHENYLYL)AZETIDIN-2-ONE PHOSPHONIC ACIDS | MICROBIA, INC. (US) | 2006-11-30 | — | — | WO | claimed |
| WO-2006122020-A2 | PROCESS FOR PRODUCTION OF 4-BIPHENYLYAZETIDIN-2-ONES | MICROBIA, INC. (US) | 2006-11-16 | — | — | WO | claimed |
| WO-2006122216-A2 | PROCESSES FOR PRODUCTION OF PHENOLIC 4-BIPHENYLYLAZETIDIN-2-ONES | MICROBIA, INC. (US) | 2006-11-16 | — | — | WO | claimed |
| EP-1363640-A4 | NUCLEIC ACID DERIVATIVES | BIO RAD LABORATORIES (US) | 2006-10-25 | — | — | EP | claimed |
| CN-1793164-A | Steroid compound with 5-alpha reductase active and preparation process thereof | UNIV TIANJIN (CN) | 2006-06-28 | — | — | CN | claimed |
| EP-1363640-A2 | NUCLEIC ACID DERIVATIVES | BIO-RAD LABORATORIES, INC. (US) | 2003-11-26 | — | — | EP | claimed |
| US-20030191074-A1 | Nucleic acid derivatives | BIO-RAD LABORATORIES INC. | 2003-10-09 | — | — | US | claimed |
| WO-2002061110-A2 | NUCLEIC ACID DERIVATIVES | BIO-RAD LABORATORIES, INC. (US) | 2002-08-08 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030191074-A1 | Nucleic acid derivatives | NSUN2, POLRMT, ADAR | KMT2A 1273/4885EPHX1 4817/4885THRB 1974/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.