Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APAF1 | O14727 | 3/20 | 0.67 |
| ▸ | TDP2 | O95551 | 2/20 | 0.67 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.65 |
| ▸ | MAPT | P10636 | 7/20 | 0.64 |
| ▸ | NPC1 | O15118 | 3/20 | 0.64 |
| ▸ | RAB9A | P51151 | 3/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.64 |
| ▸ | TP53 | P04637 | 2/20 | 0.64 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.64 |
| ▸ | MEN1 | O00255 | 7/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.61 |
| ▸ | LMNA | P02545 | 3/20 | 0.60 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.60 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.60 |
| ▸ | TSHR | P16473 | 2/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.60 |
| ▸ | GALK1 | P51570 | 2/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29630331 | 0.92 | P2RX7 (0.76) | APAF1TDP2P2RX7MAPTNPC1 | |
| Bilawsone SCHEMBL30884954 | 0.90 | APAF1 (0.75) | APAF1TDP2P2RX7MAPTNPC1 | |
| Bilawsone SCHEMBL3768549 | 0.90 | APAF1 (0.75) | APAF1TDP2P2RX7MAPTNPC1 | |
| SCHEMBL3927140 | 0.83 | P2RX7 (0.69) | APAF1TDP2P2RX7MAPTNPC1 | |
| SCHEMBL20532817 | 0.81 | APAF1 (0.89) | APAF1TDP2P2RX7MAPTNPC1 | |
| SCHEMBL461648 | 0.80 | APAF1 (1.00) | APAF1TDP2P2RX7MAPTNPC1 | |
| SCHEMBL29678361 | 0.80 | APAF1 (1.00) | APAF1TDP2P2RX7MAPTNPC1 | |
| SCHEMBL14003716 | 0.80 | CDC25B (0.73) | APAF1TDP2MAPTNPC1RAB9A | |
| SCHEMBL20963262 | 0.80 | P2RX7 (0.55) | APAF1TDP2P2RX7MAPTNPC1 | |
| SCHEMBL5280394 | 0.80 | MAPT (1.00) | APAF1TDP2P2RX7MAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230374174-A1 | Circularly Recyclable Polymers Featuring Topochemically Elongated Carbon-Carbon Bonds | PURDUE RESEARCH FOUNDATION (US) | 2023-11-23 | — | — | US | disclosed |
| US-20230374174-A1 | Circularly Recyclable Polymers Featuring Topochemically Elongated Carbon-Carbon Bonds | PURDUE RESEARCH FOUNDATION (US) | 2023-11-23 | — | — | US | disclosed |
| US-20230374174-A1 | Circularly Recyclable Polymers Featuring Topochemically Elongated Carbon-Carbon Bonds | PURDUE RESEARCH FOUNDATION (US) | 2023-11-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230374174-A1 | Circularly Recyclable Polymers Featuring Topochemically Elongated Carbon-Carbon Bonds | PCNA, PARG, VIM | APAF1 4174/4885TDP2 3211/4885P2RX7 4483/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.