SCHEMBL26656193

SCHEMBL26656193

CC(O[Si](C)(C)C(C)(C)C)C(CO)NC(=O)OC(C)(C)C

nearest known ligand 0.49

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CA1 P00915 2/20 0.49
CA2 P00918 2/20 0.49
CA7 P43166 2/20 0.49
CTSK P43235 9/20 0.38
CYP2D6 P10635 1/20 0.38
CA4 P22748 1/20 0.38
CA9 Q16790 1/20 0.38
KMT2A Q03164 1/20 0.37
CTSS P25774 4/20 0.37
TSHR P16473 1/20 0.36
HSD17B10 Q99714 1/20 0.36
L3MBTL1 Q9Y468 2/20 0.36
GAA P10253 1/20 0.36
CTSL P07711 1/20 0.35
CTSB P07858 1/20 0.35
ALDH1A1 P00352 1/20 0.35
GLS O94925 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22526271 1.00 CA1 (0.49) CA1CA2CA7CTSKCYP2D6
SCHEMBL26656189 1.00 CA1 (0.49) CA1CA2CA7CTSKCYP2D6
SCHEMBL26205581 1.00 CA1 (0.49) CA1CA2CA7CTSKCYP2D6
SCHEMBL1863352 0.85 CA1 (0.45) CA1CA2CA7CTSKCYP2D6
SCHEMBL2840815 0.83 CA1 (0.44) CA1CA2CA7CTSKCYP2D6
SCHEMBL22502687 0.82 CA1 (0.43) CA1CA2CA7CTSKCYP2D6
SCHEMBL22526363 0.82 CA1 (0.43) CA1CA2CA7CTSKCYP2D6
SCHEMBL22502689 0.82 CA1 (0.43) CA1CA2CA7CTSKCYP2D6
SCHEMBL11046024 0.82 CA1 (0.43) CA1CA2CA7CTSKCYP2D6
SCHEMBL22526366 0.82 CA2 (0.43) CA1CA2CA7CTSKCYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260001889-A1 COMPOSITIONS USEFUL FOR MODULATING SPLICING SKYHAWK THERAPEUTICS INC (US) 2026-01-01 US disclosed
WO-2023220439-A1 COMPOSITIONS USEFUL FOR MODULATING SPLICING SKYHAWK THERAPEUTICS, INC. (US) 2023-11-16 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260001889-A1 COMPOSITIONS USEFUL FOR MODULATING SPLICING SF3B1, SF3A1, SF3B5 CA1 4158/4885CA2 4095/4885CA7 4259/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.