Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.41 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9296266 | 0.84 | TRPA1 (0.52) | TRPA1TP53TDP1ALOX15HSD17B10 | |
| SCHEMBL11759062 | 0.78 | TRPA1 (0.45) | TRPA1TP53TDP1ALOX15HSD17B10 | |
| SCHEMBL18738928 | 0.77 | TDP1 (0.41) | TRPA1TP53TDP1ALOX15HSD17B10 | |
| SCHEMBL10708099 | 0.75 | ALDH1A1 (0.57) | TDP1ALOX15HSD17B10ALDH1A1LMNA | |
| SCHEMBL27263641 | 0.73 | TDP1 (0.41) | TRPA1TP53TDP1ALOX15ALDH1A1 | |
| SCHEMBL2665742 | 0.70 | ALDH1A1 (0.43) | TRPA1TP53TDP1ALOX15HSD17B10 | |
| SCHEMBL15457026 | 0.70 | NPC1 (0.33) | TRPA1TP53TDP1ALOX15ALDH1A1 | |
| SCHEMBL13461896 | 0.70 | NFE2L2 (0.35) | TRPA1TP53TDP1ALOX15ACHE | |
| SCHEMBL18883501 | 0.70 | TDP1 (0.50) | TP53TDP1ALOX15HSD17B10ALDH1A1 | |
| SCHEMBL13461647 | 0.70 | GABRA1 (0.33) | TRPA1TP53TDP1ALOX15ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002040445-A1 | GLUCAGON ANTAGONISTS/INVERSE AGONISTS | NOVO NORDISK A/S (DK) | 2002-05-23 | — | — | WO | disclosed |