Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | KDM6B | O15054 | 1/20 | 0.42 |
| ▸ | KDM4A | O75164 | 1/20 | 0.42 |
| ▸ | KDM5A | P29375 | 1/20 | 0.42 |
| ▸ | XDH | P47989 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.41 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.39 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | PANK3 | Q9H999 | 1/20 | 0.37 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.37 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.37 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2663409 | 0.76 | LMNA (0.48) | XDHEPHX2NR1H4PANK3LMNA | |
| SCHEMBL2204928 | 0.76 | HTT (0.54) | HTTALDH1A1L3MBTL1CA12CA1 | |
| SCHEMBL1449520 | 0.75 | HTT (0.65) | HTTALDH1A1L3MBTL1CA12CA1 | |
| SCHEMBL17574527 | 0.71 | — | — | |
| SCHEMBL25007242 | 0.70 | HSD17B3 (0.56) | ALDH1A1L3MBTL1S1PR2S1PR1S1PR3 | |
| SCHEMBL12788778 | 0.70 | EPHX2 (0.54) | ALDH1A1XDHEPHX2NR1H4TDP1 | |
| SCHEMBL2656129 | 0.69 | HPGD (0.37) | HTTALDH1A1L3MBTL1EPHX2NR1H4 | |
| SCHEMBL2663103 | 0.68 | ALDH1A1 (0.65) | ALDH1A1L3MBTL1EPHX2NR1H4 | |
| SCHEMBL18602133 | 0.68 | KMT2A (0.57) | ALDH1A1L3MBTL1EPHX2NR1H4MAPT | |
| SCHEMBL18235891 | 0.67 | EPHX2 (0.53) | ALDH1A1CA1CA2EPHX2NR1H4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002040445-A1 | GLUCAGON ANTAGONISTS/INVERSE AGONISTS | NOVO NORDISK A/S (DK) | 2002-05-23 | — | — | WO | disclosed |