Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2643657 | 0.82 | PTGDR2 (0.37) | HPGDHDAC1BCHEACHELMNA | |
| SCHEMBL2665699 | 0.69 | HTT (0.49) | LMNAL3MBTL1EPHX2NR1H4S1PR2 | |
| SCHEMBL2655924 | 0.65 | HPGD (0.62) | HPGDLMNANPC1KMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL28375861 | 0.64 | HPGD (0.60) | HPGDLMNANPC1KMT2AMEN1 | |
| SCHEMBL25007242 | 0.64 | HSD17B3 (0.56) | HPGDL3MBTL1KMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL2659138 | 0.64 | SMN1; SMN2 (0.35) | HPGDHDAC1HDAC6LMNAL3MBTL1 | |
| SCHEMBL3671659 | 0.63 | SMN1; SMN2 (0.43) | HDAC6L3MBTL1KMT2AMEN1EPHX2 | |
| SCHEMBL2656861 | 0.63 | MLYCD (0.47) | HPGDHDAC1HDAC6LMNAL3MBTL1 | |
| SCHEMBL2663103 | 0.62 | ALDH1A1 (0.65) | HPGDHDAC6L3MBTL1KMT2AEPHX2 | |
| SCHEMBL18602133 | 0.62 | KMT2A (0.57) | HPGDHDAC1HDAC6LMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030203946-A1 | Glucagon antagonists/inverse agonists | NOVO NORDISK A/S (DK) | 2003-10-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030203946-A1 | Glucagon antagonists/inverse agonists | GLP1R, GPR119, GCGR | HPGD 1687/4885HDAC1 2196/4885HDAC6 3661/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.