Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.46 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.46 |
| ▸ | GCGR | P47871 | 3/20 | 0.45 |
| ▸ | GIPR | P48546 | 2/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | PPARD | Q03181 | 2/20 | 0.43 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | HTR2B | P41595 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.41 |
| ▸ | USP1 | O94782 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2663337 | 0.81 | GCGR (0.55) | HDAC6HDAC8HDAC3HDAC11DEGS1 | |
| SCHEMBL2666401 | 0.81 | GCGR (0.55) | HDAC6HDAC8HDAC3HDAC11DEGS1 | |
| SCHEMBL2647028 | 0.80 | HAO1 (0.52) | HDAC6HDAC8HDAC3HDAC11DEGS1 | |
| SCHEMBL2665697 | 0.79 | GCGR (0.54) | HDAC6GCGRGIPRHDAC1OPRM1 | |
| SCHEMBL9071343 | 0.78 | GCGR (0.42) | HDAC6HDAC8GCGRGIPRHDAC1 | |
| SCHEMBL2665693 | 0.77 | GCGR (0.64) | HDAC6HDAC8HDAC3HDAC11DEGS1 | |
| SCHEMBL9071337 | 0.77 | GCGR (0.64) | HDAC6HDAC8HDAC3HDAC11DEGS1 | |
| SCHEMBL28747007 | 0.77 | OPRM1 (0.50) | HDAC6HDAC8HDAC3HDAC11DEGS1 | |
| SCHEMBL2651250 | 0.77 | GCGR (0.47) | HDAC6HDAC8HDAC3HDAC11DEGS1 | |
| SCHEMBL9071363 | 0.75 | GCGR (0.60) | GCGRGIPR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002040446-A1 | GLUCAGON ANTAGONIST/INVERSE AGONIST | NOVO NORDISK A/S (DK) | 2002-05-23 | — | — | WO | disclosed |