Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCGR | P47871 | 7/20 | 0.55 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.48 |
| ▸ | CXCR4 | P61073 | 2/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.48 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.48 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.48 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | GCG | P01275 | 2/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.44 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
| ▸ | HTR2B | P41595 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | PPARD | Q03181 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2663337 | 1.00 | GCGR (0.55) | GCGREPHX2CXCR4HDAC8HDAC6 | |
| SCHEMBL2651250 | 0.88 | GCGR (0.47) | GCGREPHX2CXCR4HDAC8HDAC6 | |
| SCHEMBL2651897 | 0.85 | MEN1 (0.52) | GCGREPHX2CXCR4HDAC8HDAC6 | |
| SCHEMBL28747007 | 0.84 | OPRM1 (0.50) | GCGREPHX2CXCR4HDAC8HDAC6 | |
| SCHEMBL2647028 | 0.83 | HAO1 (0.52) | HDAC8HDAC6HDAC3HDAC11DEGS1 | |
| SCHEMBL2665700 | 0.81 | HDAC6 (0.46) | GCGREPHX2CXCR4HDAC8HDAC6 | |
| SCHEMBL7742573 | 0.80 | CXCR4 (0.59) | GCGREPHX2CXCR4HDAC8HDAC6 | |
| SCHEMBL2665711 | 0.80 | HTR2C (0.39) | GCGREPHX2HDAC8HDAC6HDAC3 | |
| SCHEMBL2651174 | 0.79 | AGER (0.51) | GCGRHDAC1GCG | |
| SCHEMBL2663338 | 0.79 | GCGR (0.59) | GCGRCXCR4OPRM1OPRK1CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040152750-A1 | Novel glucagon antagonists | NOVO NORDISK A/S (DK) | 2004-08-05 | — | — | US | disclosed |
| WO-2004056763-A2 | NOVEL GLUCAGON ANTAGONISTS | NOVO NORDISK A/S (DK) | 2004-07-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040152750-A1 | Novel glucagon antagonists | GLP1R, GCGR, GIPR | GCGR 2/4885EPHX2 3983/4885CXCR4 2133/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.