Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.64 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.56 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.50 |
| ▸ | PPARG | P37231 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.48 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.48 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.48 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28654120 | 0.91 | SMN1; SMN2 (0.68) | SMN1; SMN2EPHX2L3MBTL1FFAR1KMT2A | |
| SCHEMBL28643603 | 0.84 | PPARG (0.67) | SMN1; SMN2EPHX2MAPTLMNARXFP1 | |
| SCHEMBL28662972 | 0.82 | MEN1 (0.58) | SMN1; SMN2EPHX2FFAR1KMT2AMEN1 | |
| SCHEMBL2912570 | 0.81 | SMN1; SMN2 (0.82) | SMN1; SMN2L3MBTL1KMT2AMEN1MAPT | |
| SCHEMBL2665739 | 0.78 | ALDH1A1 (0.57) | SMN1; SMN2L3MBTL1FFAR1KMT2AMEN1 | |
| SCHEMBL18112923 | 0.76 | MAPT (0.56) | SMN1; SMN2FFAR1MAPTRXFP1PLAAT3 | |
| SCHEMBL14531874 | 0.76 | SMN1; SMN2 (0.73) | SMN1; SMN2EPHX2L3MBTL1KMT2AMEN1 | |
| SCHEMBL13947384 | 0.76 | SMN1; SMN2 (0.73) | SMN1; SMN2EPHX2L3MBTL1KMT2AMEN1 | |
| SCHEMBL3590191 | 0.76 | SMN1; SMN2 (0.73) | SMN1; SMN2EPHX2L3MBTL1KMT2AMEN1 | |
| SCHEMBL95008 | 0.76 | SMN1; SMN2 (0.73) | SMN1; SMN2EPHX2L3MBTL1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108026028-B | Treatment of diabetes and metabolic syndrome with novel dual modulators of soluble epoxide hydrolase and peroxisome proliferator-activated receptors | 威斯康星州医药大学股份有限公司 | 2021-11-09 | — | — | CN | disclosed |