SCHEMBL26657463

SCHEMBL26657463

F/C(=C(/F)C(F)(F)F)c1ccc(-c2ccccc2)cc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 1/20 0.45
SMN1; SMN2 Q16637 4/20 0.42
MAPT P10636 2/20 0.42
WDR5 P61964 1/20 0.42
PTPN5 P54829 1/20 0.41
RAB9A P51151 2/20 0.39
NPC1 O15118 1/20 0.39
CTDSP1 Q9GZU7 1/20 0.39
BCL2L1 Q07817 2/20 0.39
MMP3 P08254 1/20 0.39
CES1 P23141 1/20 0.39
L3MBTL1 Q9Y468 2/20 0.38
PTPN1 P18031 1/20 0.38
GSK3B P49841 1/20 0.38
BAD Q92934 1/20 0.38
MEN1 O00255 1/20 0.38
POLB P06746 1/20 0.38
KMT2A Q03164 1/20 0.38
ALDH1A1 P00352 1/20 0.38
CDC25B P30305 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30662819 1.00 KIF11 (0.45) KIF11SMN1; SMN2MAPTWDR5PTPN5
SCHEMBL26657487 1.00 KIF11 (0.45) KIF11SMN1; SMN2MAPTWDR5PTPN5
SCHEMBL17885410 0.91 BCL2L1 (0.38) KIF11BCL2L1CES1PTPN1BAD
SCHEMBL14321616 0.87 CES1 (0.50) MAPTRAB9ANPC1CES1L3MBTL1
SCHEMBL10600198 0.87 CES1 (0.50) MAPTRAB9ANPC1CES1L3MBTL1
SCHEMBL10600199 0.87 CES1 (0.50) MAPTRAB9ANPC1CES1L3MBTL1
SCHEMBL25649758 0.79 BCL2L1 (0.31) BCL2L1BAD
SCHEMBL27944488 0.78 SMN1; SMN2 (0.48) KIF11SMN1; SMN2MAPTWDR5RAB9A
SCHEMBL17880805 0.76
SCHEMBL4502846 0.72 CES1 (0.75) SMN1; SMN2MAPTPTPN5RAB9ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260084134-A1 STORAGE AND DELIVERY OF GASEOUS CHEMICAL REACTANTS IN CHEMICAL PROCESSES USING METAL-ORGANIC FRAMEWORKS UNIV CORNELL (US) 2026-03-26 US disclosed
WO-2023205455-A2 STORAGE AND DELIVERY OF GASEOUS CHEMICAL REACTANTS IN CHEMICAL PROCESSES USING METAL-ORGANIC FRAMEWORKS CORNELL UNIVERSITY (US) 2023-10-26 WO disclosed
WO-2023205455-A2 STORAGE AND DELIVERY OF GASEOUS CHEMICAL REACTANTS IN CHEMICAL PROCESSES USING METAL-ORGANIC FRAMEWORKS CORNELL UNIVERSITY (US) 2023-10-26 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260084134-A1 STORAGE AND DELIVERY OF GASEOUS CHEMICAL REACTANTS IN CHEMICAL PROCESSES USING METAL-ORGANIC FRAMEWORKS ME3, ME2, SLC25A11 KIF11 1864/4885SMN1; SMN2 559/4885MAPT 1856/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.