Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 4/20 | 0.50 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | CES2 | O00748 | 2/20 | 0.36 |
| ▸ | DAO | P14920 | 1/20 | 0.36 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | F10 | P00742 | 1/20 | 0.33 |
| ▸ | F12 | P00748 | 1/20 | 0.33 |
| ▸ | F7 | P08709 | 1/20 | 0.33 |
| ▸ | F3 | P13726 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14321616 | 1.00 | CES1 (0.50) | CES1ESR1TSHRALDH1A1CES2 | |
| SCHEMBL10600198 | 1.00 | CES1 (0.50) | CES1ESR1TSHRALDH1A1CES2 | |
| SCHEMBL26657487 | 0.87 | KIF11 (0.45) | CES1ALDH1A1NPC1RAB9APTPN1 | |
| SCHEMBL30662819 | 0.87 | KIF11 (0.45) | CES1ALDH1A1NPC1RAB9APTPN1 | |
| SCHEMBL26657463 | 0.87 | KIF11 (0.45) | CES1ALDH1A1NPC1RAB9APTPN1 | |
| SCHEMBL17885410 | 0.80 | BCL2L1 (0.38) | CES1CES2PTPN1 | |
| SCHEMBL10447661 | 0.79 | CES1 (0.40) | CES1ESR1TSHRALDH1A1CES2 | |
| SCHEMBL28376070 | 0.78 | ESR1 (0.40) | ESR1TSHRALDH1A1NPC1RAB9A | |
| SCHEMBL2234110 | 0.78 | CES1 (0.47) | CES1TSHRALDH1A1CES2DAO | |
| SCHEMBL18985177 | 0.78 | CES1 (0.47) | CES1TSHRALDH1A1CES2DAO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3031851-B1 | CROSSLINKING AGENT AND FLUORINE-CONTAINING AROMATIC COMPOUND | NICHIAS CORP (JP) | 2023-10-18 | — | — | EP | disclosed |
| EP-2684859-B1 | PREPARATION METHOD FOR FLUORINE-CONTAINING OLEFINS HAVING ORGANIC-GROUP SUBSTITUENTS | UNIV OSAKA (JP) | 2023-06-14 | — | — | EP | disclosed |
| CN-114315563-A | Process for producing branched carboxylic acid compound | 常州大学 | 2022-04-12 | — | — | CN | disclosed |
| EP-2543656-B1 | METHOD FOR PRODUCING SUBSTITUTED FLUORINE-CONTAINING OLEFIN | DAIKIN IND LTD (JP) | 2019-09-25 | — | — | EP | disclosed |
| US-9242911-B2 | Preparation method for fluorine-containing olefins having organic-group substituents | OSAKA UNIVERSITY (JP) | 2016-01-26 | — | — | US | disclosed |
| US-9067200-B2 | Method for producing substituted fluorine-containing olefin | DAIKIN INDUSTRIES, LTD. (JP) | 2015-06-30 | — | — | US | disclosed |
| EP-2684859-A1 | PREPARATION METHOD FOR FLUORINE-CONTAINING OLEFINS HAVING ORGANIC-GROUP SUBSTITUENTS | Osaka University (JP) | 2014-01-15 | — | — | EP | disclosed |
| US-20130324757-A1 | PREPARATION METHOD FOR FLUORINE-CONTAINING OLEFINS HAVING ORGANIC-GROUP SUBSTITUENTS | DAIKIN INDUSTRIES (JP) | 2013-12-05 | — | — | US | disclosed |
| EP-2543656-A1 | METHOD FOR PRODUCING SUBSTITUTED FLUORINE-CONTAINING OLEFIN | Daikin Industries, Ltd. (JP) | 2013-01-09 | — | — | EP | disclosed |
| US-20120330072-A1 | METHOD FOR PRODUCING SUBSTITUTED FLUORINE-CONTAINING OLEFIN | OSAKA UNIVERSITY (JP) | 2012-12-27 | — | — | US | disclosed |
| EP-0123302-B1 | BENZOYL-UREAS EXERTING AN INSECTICIDE ACTIVITY | Montedison S.p.A. (IT) | 1989-03-01 | — | — | EP | disclosed |
| US-4594451-A | Halogen substituted | MONTEDISON S.P.A. (IT) | 1986-06-10 | — | — | US | disclosed |
| EP-0123302-A2 | Benzoyl-ureas exerting an insecticide activity | Montedison S.p.A. (IT) | 1984-10-31 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120330072-A1 | METHOD FOR PRODUCING SUBSTITUTED FLUORINE-CONTAINING OLEFIN | FOS, POF1B, FOSB | CES1 4572/4885ESR1 1205/4885TSHR 2869/4885 |
| US-20130324757-A1 | PREPARATION METHOD FOR FLUORINE-CONTAINING OLEFINS HAVING ORGANIC-GROUP SUBSTITUENTS | POF1B, OCIAD2, OGFOD1 | CES1 4764/4885ESR1 1518/4885TSHR 1609/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.