Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 4/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.33 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2666436 | 0.81 | KMO (0.38) | KMO | |
| SCHEMBL2666378 | 0.74 | SERPINE1 (0.39) | KMOEPHX2POLB | |
| SCHEMBL2656373 | 0.72 | TRPV1 (0.55) | CYP2C9TRPV1 | |
| SCHEMBL2666389 | 0.72 | TAS1R3 (0.36) | POLB | |
| SCHEMBL2656002 | 0.72 | RHOC (0.43) | — | |
| SCHEMBL2660011 | 0.72 | GCGR (0.46) | KMO | |
| SCHEMBL6755575 | 0.71 | GCGR (0.51) | EPHX2NR1H4 | |
| SCHEMBL11521484 | 0.70 | KMO (0.56) | KMO | |
| SCHEMBL2666388 | 0.70 | KMT2A (0.43) | CYP2C9CYP2C19 | |
| SCHEMBL6754632 | 0.70 | GCGR (0.48) | CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004056763-A2 | NOVEL GLUCAGON ANTAGONISTS | NOVO NORDISK A/S (DK) | 2004-07-08 | — | — | WO | disclosed |