SCHEMBL26665146

SCHEMBL26665146

[CH2]c1cc(CO)cc(CO)c1

nearest known ligand 0.48

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ ACHE P22303 1/20 0.48
▸ TSHR P16473 1/20 0.36
▸ KDM4E B2RXH2 1/20 0.36
▸ CASP6 P55212 1/20 0.36
▸ MAPT P10636 1/20 0.31
▸ RECQL P46063 1/20 0.31
▸ ENPP2 Q13822 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL63159 0.83 ACHE (0.62) ACHETSHRKDM4ECASP6MAPT
SCHEMBL28917348 0.82 CYP4F2 (0.44) ACHEKDM4ECASP6
SCHEMBL9066971 0.77 TDP1 (0.42) TSHRKDM4EMAPT
SCHEMBL27618715 0.77 DAO (0.43) TSHRMAPT
SCHEMBL28116263 0.75 ACHE (0.48) ACHETSHRKDM4ECASP6MAPT
SCHEMBL28093078 0.73 SMN1; SMN2 (0.41) TSHRKDM4EMAPTRECQL
SCHEMBL9999570 0.73 ACHE (0.53) ACHETSHRKDM4ECASP6MAPT
SCHEMBL20649211 0.73 ACHE (0.53) ACHETSHRKDM4ECASP6MAPT
SCHEMBL231469 0.73 — —
SCHEMBL30539351 0.71 ACHE (0.50) ACHETSHRKDM4ECASP6MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106279162-A One-dimensional organic semiconductor nanowires/band that organophosphorus compound toxic gas is had fluorescence response and its preparation method and application 中国科学院化学研究所 2017-01-04 — — CN claimed
US-20240115511-A1 NANOMATERIALS COMPRISING AN IONIZABLE LIPID BEAM THERAPEUTICS INC. 2024-04-11 — — US disclosed
EP-4281050-A1 NANOMATERIALS Beam Therapeutics Inc. (US) 2023-11-29 — — EP disclosed
EP-4281064-A1 NANOMATERIALS COMPRISING AN IONIZABLE LIPID Beam Therapeutics Inc. (US) 2023-11-29 — — EP disclosed
CN-106279162-A One-dimensional organic semiconductor nanowires/band that organophosphorus compound toxic gas is had fluorescence response and its preparation method and application 中国科学院化学研究所 2017-01-04 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240115511-A1 NANOMATERIALS COMPRISING AN IONIZABLE LIPID LIPA, SGMS2, PHOSPHO1 ACHE 2875/4885TSHR 3172/4885KDM4E 4244/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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